参麦注射液对慢性肺源性心脏病患者血流功能状况影响的实验观察

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Abstract Objective To observe the influence of Shenmai Injection on blood flow function in patients with chronic pulmonary heart disease.Methods 124 patients (volunteers) with chronic pulmonary heart disease treated in department of clinical laboratory of our hospital from January 2014 to November 2015 were randomly divided into control group and experimental group.62 cases of control group were treated with conventional western medicine treatment such as control infection,strong heart,diuretic,smooth wheezing expectorant,low flow oxygen,correct electrolyte and acid-base balance disorder and so on.The experimental group (n=62) was treated with conventional western medicine combined Shen-mai Injection.The course of the treatment were 14 days.Blood flow function indexes (blood rheology,haematocrit and fibrinogen) were determined before and after treatment in two groups.Results After treatment,the whole blood high shear reductive viscosity [(7.86±1.28),(7.71±1.11) mPa·s] whole blood low shear reduction viscosity [(54.96±9.43),(49.00±4.51) mPa·s],plasma viscosity [(1.88±0.28),(1.43±0.18) mPa·s],fibrinogen [(2.50±1.11),(2.05±1.13) g/L] and hematocrit[(0.45±0.09),(0.43±0.04) L/L] in control group and experimental group were improved compared with before treatmenrt (P<0.05).The treatment group showed the improved significantly better than the control group except the whole blood high shear reductive viscosity (P<0.05). Conclusion On the basis of conventional western medicine treatment,Shenmai Injection added treating chronic pulmonary heart disease can obviously improve blood flow function indexes of patients,and it may be has an positive meaning for long term stablely control of patients′ condition and reduce the occurrence of complications.

Key words： Shenmai Injection Chronic pulmonary heart disease Hemorheology

Received: 24 March 2017

PACS:

R541.5

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	YANG Jian
	LAN Dan

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YANG Jian,LAN Dan. Experimental observation on the influence of Shenmai Injection on blood flow function in patients with chronic pulmonary heart disease[J]. 中国当代医药, 2017, 24(24): 109-111.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I24/109

[1]	李广斌.慢性肺源性心脏病发病机制及治疗靶点研究进展[J].天津医科大学学报,2014,20（2）：162-164.
[2]	贾佳,程德云.慢性阻塞性肺疾病相关肺动脉高压发病机制[J].临床荟萃,2016,31（3）：345-348.
[3]	]喻兰芬.老年慢性肺源性心脏病诊治分析[J].实用心脑肺血管病杂志,2011,19（5）：808-809.
[4]	胡蕊,王志峰,王冉,等.慢性肺源性心脏病患者心理健康状况的调查及生活质量影响因素的分析[J].河北医药,2013, 35（9）：1393-1394.
[5]	任立新,梅少奇.红花黄色素注射液治疗AECOPD合并慢性肺源性心脏病患者疗效观察[J].临床肺科杂志,2014, 19（6）：1039-1041.
[6]	汤学勤,武雪亮,项保利,等.呋塞米联合依那普利对慢性肺源性心脏病心力衰竭的临床研究[J].中国临床药理学杂志,2016,32（3）：198-201.
[7]	袁连方,戴璇.红花黄色素对肺心病患者血小板CD62P表达、血浆D-dimer水平的影响及意义[J]. 山东医药,2015, 55（28）：86-87
[8]	尹晓姝,彭俊,钟琳玲,等.88例老年慢性肺源性心脏病合并冠心病的临床探析[J].当代医学,2015,21（35）：97-98.
[9]	赵娟.15例慢性肺源性心脏病右心衰竭合并肺栓塞临床特点[J].中国实用医药,2016,11（1）：82-83.
[10]	解拥军.慢性肺源性心脏病血液流变学的检测与分析[J].检验医学与临床,2013,10（10）：1309-1311.
[11]	薛志芳,汤亚琴.参麦注射液对老年肺心病血液流变学和血气分析影响的相关性研究[J].中国血液流变学杂志,2005,15（2）：258-259.
[12]	崔彩梅,丁连明.参麦注射液对肺心病患者血液流变学的影响[J].四川医学,2009,30（2）.235-236.
[13]	汪周华.中西医结合治疗慢性肺源性心脏病疗效观察[J].现代中西医结合杂志,2016,25（20）：2230-2232.
[14]	李素引,高秀玲,张菊香.参麦注射液治疗慢性肺源性心脏病患者的疗效观察[J].临床肺科杂志,2012,17（7）：1214-1215.
[15]	王永,刘勇,朱宝山,等.参麦注射液联合无创双水平气道正压通气治疗老年慢性肺源性心脏病合并心力衰竭的临床疗效及对血清D-二聚体和N-末端脑利钠肽前体水平的影响[J].实用心脑肺血管病杂志,2015,23（10）：112-114,117.