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| Clinical study of lymphocyte injection combined with oral administration of progesterone in the treatment of alloimmune recurrent abortion |
| LONG Cheng-ying XU Shan-shan |
| Renkang Hospital of Dongguan,Guangdong Province,Dongguan 523952,China |
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Abstract ObjectiveTo study the clinical effect of lymphocyte injection combined with oral administration of progesterone in the treatment of alloimmune recurrent abortion.MethodsTwo hundred patients were randomly selected from January 2015 to January 2016 in our hospital with negative closed antibodies for recurrent abortion and the same kind of immunity,and were randomly divided into the control group and the study group equally.The patients of the study group was given the injection of lymphocyte and when pregnancy for progesterone plus;the patients of the control group, pregnancy was given lymphocyte injection combined with oral dydrogesterone.At the same time,patients of the two groups were regularly followed up to observe with pregnancy success rate and pathological pregnancy rate.ResultsAfter the corresponding treatment,patients with the positive situation of the two groups was more obvious,but the difference between the positive and negative cases was not significant(P＞0.05).Patients with greater or equal to 12 weeks pregnancy were successful,the success rate of pregnancy of the study group(80.0%)was significantly higher than that of the control group (62.0%),the difference was statistically significant(χ2=17.267,P=0.018).ConclusionThe preinjection of lymphocytes,pregnancy plus oral dydrogesterone in the treatment of patients with alloimmune recurrent spontaneous abortion,improve the cell immune status in vivo,has good curative effect.
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