比索洛尔联合依那普利、螺内酯治疗风湿性心脏病慢性心力衰竭的效果观察

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Abstract ObjectiveTo observe and compare the efficacy of Bisoprolol and Enalapril combined with Spironolactone in the treatment of rheumatic heart disease patients with chronic heart failure.MethodsFrom June 2015 to June 2016,94 patients with rheumatic heart disease and chronic heart failure were selected as study objects and randomly divided into experimental group and control group,47 cases in each group.The patients in the control group were given routine drug treatment,while patients in the experimental group were treated with Bisoprolol and Enalapril combined with Spironolactone.The therapeutic effect of two groups were observed and compared.ResultsAfter treatment,the total effective rate in the experimental group was 95.75%(45/47),which was significantly higher than 82.98%(39/47)in the control group,and the difference was statistically significant(P＜0.05).The LVESD,LVEDD and LVEF of the experimental group was significantly better than that of the control group,and the difference was statistically significant(P＜0.05).ConclusionThe combination of Bisoprolol,Enalapril and Spironolactone is effective in the treatment of rheumatic heart disease with chronic heart failure.It is worthy to be further studied and applied.

Key words： Bisoprolol Enalapril Spironolactone Rheumatic heart disease Chronic heart failure

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	Articles by authors
	XIE Guo-bo
	ZHONG Yan-jia
	SHENG Guo-tai
	YU Mao-Sheng
	YANG Ming

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XIE Guo-bo,ZHONG Yan-jia,SHENG Guo-tai, et al. Effect of Bisoprolol combined with Enalapril and Spironolactone in the treatment of rheumatic heart disease patients with chronic heart failure[J]. 中国当代医药, 2016, 23(35): 49-51.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2016/V23/I35/49

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