右美托咪定在ICU心力衰竭患者中的临床应用

Abstract
Figure/Table
References (15)
Related Citation (15)

Download: PDF (0 KB) HTML (38 KB)
Export: BibTeX | EndNote (RIS)

Abstract ObjectiveTo explore the application effect of Dexmedetomidine in ICU patients with heart failure.Methods54 patients with heart failure who were admitted to our hospital from October 2015 to February 2016 were selected and divided into the observation group(n=28)and the control group(n=26)according to the different sedative and analgesic drugs.The observation group was given Dexmedetomidine,the control group was given Propofol.The condition of improvement and prognosis were compared between the two groups.ResultsThe level of CK-MB,MYO,PaCO2after 24 hours in the two groups was lower than that before entering ICU,with significant difference (P＜0.05).The level of CKMB,MYO,PaCO2after 24 hours in the observation group was lower than that in the control group,with significant difference(P＜0.05).The APACHEⅡscore of the observation group after treatment was higher than that of the control group, and the Ramsay score of the observation group after treatment was lower than that of the control group,with significant difference(P＜0.05).The mortality rate of the observation group in 3 days was 10.7%,which was lower than 19.2%of the control group,with significant difference(P＜0.05).ConclusionThe application of Dexmedetomidine in ICU patients with heart failure,can promote the recovery of myocardial function,effectively alleviate the symptoms of heart failure,improve the prognosis of patients.

Key words： ICU Heart failure Dexmedetomidine Cardiac function Prognosis

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	ZHU Yun-lin
	ZHU Hua-yong
	ZHANG Wei-wei

Cite this article:

ZHU Yun-lin,ZHU Hua-yong,ZHANG Wei-wei. Clinical application of Dexmedetomidine in patients with heart failure in ICU[J]. 中国当代医药, 2017, 24(2): 116-118.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I2/116

[1]	汪晓波，吴蓓蕾，林莉，等.右美托咪定在呼吸衰竭患者无创通气的临床疗效[J].解放军药学学报，2014，30（5）：472-474.
[2]	张磊，石斌，李斌，等.盐酸右美托咪定对机械通气患者镇静的效果与安全性[J].兰州大学学报（医学版），2013，39（4）：58-60.
[3]	Lu X，Li J，Li T，et al.Clinical study of midazolam sequential with dexmedetomidine for agitated patients undergoing weaning to implement light sedation in intensive care unit [J].Chin J Traumatol，2016，19（2）：94-96.
[4]	胡谟文.右美托咪定不同给药方式对下肢骨科术后镇痛效应的影响[J].中国医药科学，2016，6（1）：165-167，183.
[5]	叶嘉，林庆安，张雷，等.右美托咪定在AECOPD合并呼吸衰竭患者无创机械通气时镇静治疗及文献回顾[J].临床肺科杂志，2013，18（7）：1178-1180.
[6]	Mohamed AA，Fares KM，Mohamed SA.Efficacy of intrathecally administered dexmedetomidine versus dexmedetomidine with fentanyl in patients undergoing major abdominal cancer surgery.[J].Pain Physician，2012，15（4）：339-348.
[7]	李永波，梅啸，黄远贞，等.单一剂量右美托咪定在慢性阻塞性肺病患者撤机中的应用[J].内科急危重症杂志，2012，18（3）：145-147.
[8]	胡超娅，周文玲.右美托咪定用于急性左心衰无创正压通气效果观察[J].实用中医药杂志，2014，30（8）：762-764.
[9]	袁俊，何文宗，周咏，等.右美托咪定、咪达唑仑对急性左心衰竭机械通气患者的镇静作用[J].山东医药，2014，54（1）：59-60.
[10]	张瑶，李伟彦.右美托咪定临床应用的研究进展[J].医学综述，2013，19（4）：693-695.
[11]	王道伟，王芬梅，韩艳敏，等.右美托咪定对心肌梗死围PCI手术期临床镇静疗效观察[J].临床合理用药杂志，2014，7（28）：24-25.
[12]	张卫，周立君，阚全程，等.不同剂量右美托咪定与小剂量氯胺酮预防瑞芬太尼复合麻醉后痛觉过敏的效果比较[J].临床麻醉学杂志，2013，29（5）：435-438.
[13]	王舜尧，祝利华.右美托咪定和咪达唑仑复合芬太尼对ICU术后机械通气患者镇静的影响[J].实用药物与临床，2014，17（3）：308-310.
[14]	丁喜珍，常宁，葛雪.机械通气联合右美托咪定治疗左心衰的疗效观察[J].青岛医药卫生，2012，44（5）：363-364.
[15]	张加强，张卫.右美托咪定对心脏瓣膜置换术患者的心肌保护作用[J].临床麻醉学杂志，2014，30（5）：426-429.