大黄芒硝散外敷联合常规抗感染治疗在剖宫产术后腹壁切口感染、裂开患者中的应用

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Abstract Objective To analyze the clinical effect of Rhubarb-Mirabilite Powder combined with conventional anti-infective treatment in patients with abdominal wall incision infection or dehiscence after cesarean section. Methods A total of 87 patients with abdominal wall incision infection or dehiscence after cesarean section treated in the Affiliated Suzhou Hospital of Nanjing Medical University (Suzhou Municipal Hospital) from January 1, 2018 to December 31,2020 were selected for retrospective analysis. According to their treatment methods, they were divided into the control group (43 cases) and the observation group (44 cases). The control group received anti-infection and conventional dressing change. The observation group received anti-infection and conventional dressing change treatment, and external application of Rhubarb-Mirabilite Powder was given to the incisions additionally. The incision healing grade, bacterial culture negative time, induration disappearance time, incision complete healing time, hospitalization time, inflammatory factor indexes (C-reactive protein [CRP], procalcitonin [PCT], white blood cell count [WBC]), the re-debridement and suture rate were compared between the two groups. Results The incision healing grade of the observation group was better than that of the control group, and the difference was statistically significant (P＜0.05). The bacterial culture negative time, induration disappearance time, incision complete healing time, hospitalization time in the observation group were shorter than those in the control group, and the differences were statistically significant (P＜0.05). After one week of treatment, the levels of CRP, PCT and WBC in the observation group were lower than those in the control group, and the differences were statistically significant (P＜0.05). After 2 weeks of treatment, there was no significant difference in the levels of CRP, PCT and WBC between the two groups (P＞0.05). The rate of re-debridement and suture in the observation group was lower than that in the control group, and the difference was statistically significant (P＜0.05). Conclusion The external application of Rhubarb-Mirabilite Powder combined with conventional anti-infective treatment can effectively promote the healing of infected incisions after cesarean section, reduce the rate of re-debridement and suture, and shorten the hospitalization time.

Key words： Cesarean section Infection Dehiscence Rhubarb-Mirabilite Powder

Received: 16 August 2021

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I35/140

[1]	彭静，陈雅颂，梁月梅，等.阴道助产对剖宫产术后阴道分娩母婴结局的影响[J].中华产科急救电子杂志，2020，9（3）：180-185.
[2]	陈娟娟，陈敦金.剖宫产手术并发子宫切口感染[J].中国实用妇科与产科杂志，2019，35（2）：167-171.
[3]	龚星星.甲硝唑溶液冲洗宫腹腔与头孢唑林钠联用预防剖宫产术患者术后切口感染的疗效评价[J].抗感染药学，2019，16（1）：118-120.
[4]	刘琴.剖宫产产妇术后切口感染的危险因素及病原菌特点分析[J].临床医药文献电子杂志，2020，7（21）：10，12.
[5]	李妍，李娜.剖宫产切口感染的高危因素分析及预防策略[J].中国妇幼保健，2017，32（21）：5195-5198.
[6]	鄢贵芹.大黄芒硝促进剖宫产术后切口愈合临床疗效观察[J].实用妇科内分泌电子杂志，2019，6（15）：127-128.
[7]	林震群，黄泽辉，周文博.大黄芒硝散外敷对重症急性胰腺炎肠功能障碍患者肠功能的影响[J].中国医院用药评价与分析，2019，19（8）：937-939.
[8]	马晓平，赵万霞，刘燕芳，等.浅谈大黄芒硝散药袋外敷预防开腹术后切口液化临床疗效[J].临床医药文献电子杂志，2019，6（93）：57.
[9]	Ben Shoham A，Bar-Meir M，Ioscovich A，et al.Timing of antibiotic prophylaxis in cesarean section：retrospective，difference-in-differences estimation of the effect on surgicalsite-infection[J].J Matern Fetal Neonatal Med，2019，32（5）：804-808.
[10]	张凯，苏禹，宋红艳，等.剖宫产术后产褥感染的病原菌分布、耐药性及PCT、CRP 水平变化[J].实验与检验医学，2021，39（3）：680-683，693.
[11]	Tan X，Liu S，Song L，et al.Effects of antibiotics on prevention of infection，white blood cell counts，and C-reactive protein levels at different times in the perioperative period of cesarean section[J].Int J Clin Pharmacol Ther，2020，58（6）：310-315.
[12]	史扬，庞立彦，罗晓华，等.急诊剖宫产术后切口感染危险因素分析[J].中国实验诊断学，2021，25（7）：994-997.
[13]	李晶晶.大黄芒硝外敷促进剖宫产术后腹部切口愈合的效果[J].北方药学，2019，16（5）：151，160.
[14]	沈建良，潘良明，孔祥东，等.大黄芒硝散外敷治疗大鼠阑尾周围脓肿的实验研究[J].中国医药导报，2017，14（12）：151-154.
[15]	朱紫芹.剖宫产产妇术后切口感染的病原菌特点及危险因素分析[J].中国卫生检验杂志，2019，29（9）：1105-1107.
[16]	李晓慧.甲硝唑注射液冲洗对降低剖宫产术后切口感染和产褥感染发生率的影响[J].临床医药文献电子杂志，2020，7（12）：33-34.
[17]	顾燕娜，江起庭.芒硝外敷对乳腺良性肿块麦默通微创旋切术后疼痛及血肿的影响[J].中国烧伤创疡杂志，2019，31（1）：41-45.
[18]	冯秀芹.大黄芒硝外敷法联合硫酸镁湿敷法在会阴侧切术后切口肿痛中的应用[J].光明中医，2020，35（10）：1550-1552.