厄贝沙坦氢氯噻嗪联合比索洛尔治疗慢性心力衰竭合并房性或室性心律失常患者的临床效果

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Abstract Objective To investigate the clinical effect of Irbesartan Hydrochlorothiazide combined with Bisoprolol in the treatment of chronic heart failure complicated with atrial or ventricular arrhythmias.Methods A total of 60 patients with chronic heart failure complicated with atrial or ventricular arrhythmia treated in Linchuan District People′s Hospital of Fuzhou City,Jiangxi Province from January 2016 to January 2020 were selected as the research objects and divided into the control group and study group by random number table method,with 30 cases in each group.The control group was treated with Bisoprolol,and the study group was treated with Irbesartan Hydrochlorothiazide combined with Bisoprolol.The clinical efficacy,cardiac function and incidence of adverse reactions were compared between the two groups.Results The total effective rate of the study group was higher than that of the control group,and the difference was statistically significant(P＜0.05).There were no statistically significant differences between the control group before and after treatment in terms of interventricular septal thickness (IVST),left ventricular posterior wall thickness(LVPWT)and left ventricular ejection fraction(LVEF)(P＞0.05).The IVST and LVPWT in the study group after treatment were lower than those before treatment,and LVEF was higher than that before treatment,the differences were statistically significant(P＜0.05).After treatment,IVST and LVPWT in the study group were lower than those in the control group,and LVEF was higher than that in the control group,the differences were statistically significant(P＜0.05).There was no statistically significant difference in the total incidence of adverse reactions between the two groups(P＞0.05).Conclusion Irbesartan Hydrochlorothiazide combined with Bisoprolol can effectively inhibit myocardial remodeling in patients with chronic heart failure complicated with atrial or ventricular arrhythmia,which is safe,effective and worthy of clinical promotion.

Key words： Cardiac function Arrhythmia Chronic heart failure Bisoprolol Irbesartan Hydrochlorothiazide

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	QIU De-he

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QIU De-he. Clinical effect of Irbesartan Hydrochlorothiazide combined with Bisoprolol in the treatment of chronic heart failure complicated with atrial or ventricular arrhythmia[J]. 中国当代医药, 2021, 28(31): 63-66.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I31/63

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