|
|
Clinical effect of Sertraline oral combined with Morita therapy in the treatment of obsessive-compulsive disorder |
LUAN Lei1WANG Yan-ru2▲ |
1.Department of Psychology,the Fourth People′s Hospital of Yingkou City,Liaoning Province,Yingkou 115000,China;
2.Department of Oncology,Anshan Tumor Hospital,Liaoning Province,Anshan 114000,China |
|
|
Abstract Objective To investigate the clinical effect of Sertraline oral combined with Morita therapy in the treatment of obsessive-compulsive disorder(OCD).Methods A total of 94 patients with obsessive-compulsive disorder admitted to the Fourth People′s Hospital of Yingkou City from April 2019 to April 2020 were selected and divided into a study group and a reference group according to a random lottery method,with 47 cases in each group.The clinical efficacy of the two groups was compared.The Yale-Brown obsessive compulsive scale (YBOCS)and Hamilton anxiety scale(HAMA)were used to evaluate the improvement of obsessive-compulsive symptoms and anxiety before and after treatment in the two groups.The social disability screening scale (SDSS)was used to evaluate the improvement of social function in the two groups.Results The treatment total effective rate of the study group was higher than that of the reference group,and the difference was statistically significant(P<0.05).Before treatment,there was no statistically significant difference between the YBOCS and HAMA scores of the two groups (P>0.05);after treatment,the YBOCS and HAMA scores of the two groups were lower than before treatment,the YBOCS and HAMA scores of the study group were lower than those of the reference group,and the differences were statistically significant(P<0.05).Before treatment,there was no statistically significant difference in SDSS scores between the two groups(P>0.05);six months after treatment,the SDSS scores of the two groups was higher than before treatment,the difference was statistically significant(P<0.05),and the SDSS score of study group was higher than that of the reference group,the difference was statistically significant(P<0.05).Conclusion The application of Sertralin combined with Morita therapy in patients with obsessive-compulsive disorder can promote the improvement of patients′obsessive-compulsive symptoms and anxiety,improve clinical efficacy,and contribute to the enhancement of patients′social function.
|
|
|
|
|
[1] |
朱笑,袁心崧,施慎逊.基于PET技术的强迫症大脑功能、代谢改变研究进展[J].山东医药,2019,59(8):111-113.
|
[2] |
冉冰娜,秦伟杰.药物治疗联合心理护理对改善强迫症患者症状的疗效观察[J].医药界,2020,22(16):7.
|
[3] |
姜丽艳,黄晓敏.阿立哌唑联合氟伏沙明治疗强迫症的临床疗效安全性及对患者生存质量的影响分析[J].心理月刊,2019,14(16):26-27.
|
[4] |
肖伟霞,廖鹰,杜明君,等.抗抑郁药物联合短程团体认知行为疗法治疗强迫症临床观察[J].国际精神病学杂志,2019,46(4):663-665,668.
|
[5] |
张俊峰,戴炜,郭青山,等.改良森田疗法治疗焦虑障碍临床疗效研究[J].神经损伤与功能重建,2019,14(8):418-420.
|
[6] |
涂小波.舍曲林合并门诊式森田疗法治疗强迫症疗效观察[J].重庆医学,2017,22(46):366-367.
|
[7] |
卜琴芳,陈方斌.阿立哌唑联合舍曲林治疗强迫症患者的疗效及对脑源性神经营养因子TNFIL-2水平的影响[J].河北医学,2019,21(10):45-47.
|
[8] |
中华医学会精神科分会.CCMD-3中国精神障碍分类与诊断标准[M].山东科学技术出版社,2001:45.
|
[9] |
Storch EA,Larson MJ,Price LH,et al.Psychometric analysis of the Yale-Brown Obsessive-Compulsive Scale Second Edition Symptom Checklist[J].J Anxiety Disord,2010,24(6):650-656.
|
[10] |
Hamilton M.The assessment of anxiety states by rating[J].Br J Med Psychol,1959,32(16):50-55.
|
[11] |
刁维东,王金柱,李永红.奥氮平片联合氯丙咪嗪治疗难治性强迫症的疗效及对安全性分析[J].河北医学,2019,25(5):123-128.
|
[12] |
房艳艳,周伟,徐其涛.内观疗法联合改良森田疗法对广泛性焦虑障碍患者的疗效[J].中国健康心理学杂志,2019,27(8):1141-1145.
|
[13] |
王云,陈永新,张子梅.天智颗粒联合氟伏沙明治疗青少年强迫症的临床观察[J].中国现代应用药学,2019,36(6):99-102.
|
[14] |
李锦棉,宋妍,李子欢.改良森田疗法联合生物反馈治疗焦虑症疗效分析[J].临床医药文献电子杂志,2020,7(32):12-13.
|
[15] |
冯文君,李秀,李江波.森田疗法治疗强迫症疗效的Meta分析[J].神经疾病与精神卫生,2019,19(9):888-893.
|
[16] |
杨保平,黄贯峰,崔小利,等.文拉法辛缓释片联合改良森田疗法对精神分裂症阴性症状患者精神状态及阴性症状的影响[J].包头医学院学报,2020,36(10):62-63,111.
|
[17] |
王海龙.森田疗法联合文拉法辛治疗强迫症患者的效果[J].中国民康医学,2020,32(6):87-89.
|
[18] |
侯景英,卢建国,孔辉,等.森田疗法联合舍曲林治疗强迫症患者的短期临床研究[J].国际精神病学杂志,2019,46(2):82-84,94.
|
|
|
|