Abstract：Objective To observe the clinical efficacy of Flamigel combined with external recombinant human granulocyte-macrophage stimulating factor gel on treating levelⅡdeep burn.Methods From May 2016 to May 2017,103 patients with levelⅡdeep burn treated in our hospital were selected as research objects.By odd or even numbers and computerized randomization,they were divided into control group(n=51)and observation group(n=52).Besides smearing recombinant human granulocyte-macrophage stimulating factor gel on the wound,external application of sulfadiazine silver cream and Flamigel gauze was used in the control group and observation group respectively.The wound healing rate,healingtime,bacterialculture,and adverse reaction were observed in both groups.Results With the time prolonging,the healing rate in the two groups was increased,but the rate in the observation group was higher(P<0.05).The average healing time was(24.5±3.8)d in the observation group,shorter than that in the control group,(29.6±4.7)d.There was no significant difference in the positivity rate of bacterial culture within one week between the two groups(P＞0.05).No obvious adverse reactions of the skin or abnormal liver and kidney functions was displayed.Conclusion Combination of Flamigel andexternal recombinant human granulocyte-macrophage stimulating factor gel can obtain a remarkable effect on treating levelⅡdeep burn,which is worthy of promotion in clinic.
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