Objective To explore the value of urine sediment analyzer combined with urine dry chemistry method for urine white blood cell detection. Methods A total of 500 cases of urine specimens from the Third People′s Hospital of Yichun City in Jiangxi Province from January to June 2019 were collected and divided into the control group(n=250)and the observation group (n=250) according to the randomized double-blind method.Urine dry chemical method was used in the control group,and urine sediment analyzer combined with urine dry chemical method was used in the observation group.Urine sediment microscopic examination was used as gold standard,the positive rate,missed diagnosis rate and misdiagnosis rate of urine leucocytes were compared between the two groups.Results The results of urine sediment microscopy showed that the urine leukocyte positive rate of the control group was 79.20% (198/250)，and the urine leukocyte positive rate of the observation group was 77.60%(194/250).There was no significant difference in the positive rate of urine leukocytes between the two groups (P＞0.05).The positive rate of urine leucocytes detected by the test method in the observation group was 76.00% (190/250),which was higher than that in the control group (56.00%) (140/250),and the difference was statistically significant (P＜0.05).The coincidence rate of urine white blood cells detected in the urine samples of the observation group was higher than that of the control group,and the missed diagnosis rate and misdiagnosis rate in the urine samples of the observation group were lower than those of the control group,and the differences were statistically significant(P＜0.05).Conclusion Urine sediment analyzer combined with urine dry chemistry method can reduce the missed diagnosis rate and misdiagnosis rate of urine leukocyte detection,and improve the detection value.