Analysis of birth defects of gestational age less than 28 weeks in Fujian Province from 2018 to 2020
LIN Ying-ying1ZHU Wen-bin1LIN Juan2XIU Xiao-yan2YAN Jian-ying2▲
1.Department of Healthcare,Fujian Maternity and Child Health Hospital,Affiliated Hospital of Fujian Medical University,Fujian Province,Fuzhou 350001,China;
2.Department of Obstetrics,Fujian Maternity and Child Health Hospital,Affiliated Hospital of Fujian Medical University,Fujian Province,Fuzhou 350001,China
Abstract：Objective To analyze the birth defects of gestational age less than 28 weeks in Fujian Province from 2018 to 2020,and provide basis for comprehensive prevention and treatment of birth defects.Methods Clinical data of perinatal infants from 103 hospitals in the birth defect surveillance system of Fujian Province from January 2018 to December 2020 were collected,and various data of birth defects of gestational age less than 28 weeks were statistically analyzed.Results From 2018 to 2020,a total of 795 475 perinatal infants and 31 475 birth defects were monitored,of which 7241 cases had a gestational age less than 28 weeks (23.01%).The therapeutic induction rate of infants with birth defects of gestational age less than 28 weeks was 97.51%.Most malformation was diagnosed prenatally and mainly based on ultrasound or chromosomes,with the main outcome was generally stillbirth.Birth defects of gestational age less than 28 weeks differed greatly in maternal age,usual residence and fetal gender.The incidence of birth defects was higher among women with advanced age,urban residents and male infants,with the differences were statistically significant(P<0.001).The five major types of birth defects of gestational age less than 28 weeks were congenital heart disease,the cleft lip with or without cleft palate,Down′s syndrome,neural tube defects and umbilical bulge.Conclusion Birth defects of gestational age less than 28 weeks are mainly severely lethal and disabling birth defects.Comprehensive consideration,along with prevention and control strategies,should be given to the characteristics of birth defects of different gestational ages.
林英英；朱文斌；林 娟；修晓燕；颜建英. 2018—2020年福建省孕28周以下出生缺陷儿的情况分析[J]. 中国当代医药, 2021, 28(32): 180-183.
LIN Ying-ying；ZHU Wen-bin；LIN Juan；XIU Xiao-yan；YAN Jian-ying. Analysis of birth defects of gestational age less than 28 weeks in Fujian Province from 2018 to 2020. 中国当代医药, 2021, 28(32): 180-183.
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