多巴胺+酚妥拉明治疗急诊重症肺炎合并心力衰竭的效果

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Abstract Objective To analyze the effect of Dopamine and Phentolamine in emergency severe pneumonia with heart failure.Methods A total of 54 children with severe pneumonia complicated with heart failure treated in the Hospital of Shunyi District of Beijing from February 2018 to February 2020 were selected as the research subjects.According to random number table method,they were divided into control group (27 cases) and experimental group (27 cases).The control group was treated with Dopamine,and the experiment group was treated with the combination of Dopamine and Phentolamine.The clinical total effective rates,inflammatory factor levels and cardiac functions of the two groups were compared.Results The total effective rate of the experiment group was higher than that of the control group,with statistically significant difference (P<0.05).Before treatment,the differences of C-reactive protein (CRP),tumor necrosis factor α (TNF-α),interleukin-6 (IL-6) levels between the two groups were not statistically significant (P>0.05).After treatment,the levels of CRP,TNF-α and IL-6 in the two groups were lower than those before treatment,while the levels of CRP,TNF-α and IL-6 in the experimental group were lower than those in the control group,with statistically significant differences (P<0.05).After treatment,the heart rate and left ventricular end diastolic diameter of the two groups were lower than those before treatment,and the left ventricular ejection fraction was higher than that before treatment,and the differences were statistically significant (P<0.05).Heart rate and left ventricular end diastolic diameter in experimental group were lower than those in control group,and left ventricular ejection fraction was higher than that in control group,with statistically significant differences (P<0.05).Conclusion Dopamine and Phentolamine was more effective than monotherapy in the treatment of emergency severe pneumonia with heart failure.

Key words： Dopamine Phentolamine Emergency severe pneumonia Heart failure

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	LU Jian-guang

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LU Jian-guang. Effect of Dopamine and Phentolamine in emergency severe pneumonia with heart failure[J]. 中国当代医药, 2021, 28(4): 48-50.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I4/48

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