妊娠期代谢综合征对母儿脂代谢的影响研究

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Abstract ObjectiveTo study the effects of metabolic syndrome during pregnancy on lipid metabolism in pregnant women and the effects on the early lipid metabolism in their offspring.MethodsA total of 40 pregnant women who were hospitalized and gave delivery in the department of obstetrics in the Affiliated Hospital of Weifang Medical University from May 2016 to May 2017 were selected.Among them,20 cases of the pregnant women with metabolic syndrome in pregnancy and 20 offsprings of theirs were assigned to the study groups.20 healthy pregnant women and their offsprings were assigned to the control groups.The levels of apolipoprotein E,adiponectinand leptin in the serum of pregnancy women were measured respectively.At the same time,the correlation analysis between the above three components in the umbilical cord serum of the offspring were carried out.ResultsApolipoprotein E was　(490.15±90.76)ng/ml and leptin was(4.92±1.00)ng/ml in the pregnancy women in the study group.The Apolipoprotein was(576.95±83.37)ng/ml and leptin was　(3.16±1.18)ng/ml in their offsprings,which were all higher than those in the control group for pregnant women,apolipoprotein E and leptin were(389.51±69.37)ng/ml and(3.83±0.52)ng/ml respectively,and for the offsprings,the apolipoprotein E and leptin were(400.38±57.25)ng/ml and(2.29±1.01)ng/ml respectively;adiponectin was(4.76±1.19)ng/ml in the pregnancy women in the study group,and adiponectin was(4.29±1.34)ng/ml in their offsprings,which were both lower than those in the control group(adiponectin was[7.63±2.77]ng/ml in the pregnant women,and the adiponectin was　[6.32±1.97]ng/ml in the offsprings).The differences were statistically significant(P<0.05).ConclusionMetabolic syndrome during pregnancy leads to abnormal lipid metabolism in pregnant women and affects early lipid metabolism in the offsprings,which increases the risk of future metabolic syndrome in the offsprings.

Key words： Metabolic syndrome during pregnancy Apolipoprotein E Adiponectin Leptin Lipid metabolism

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	Articles by authors
	LI Xiu-ming
	JI Jia-fen
	LIU Chang-yun
	ZHU Hai-ling
	ZHANG Qi
	ZHAI Yu-ping
	ZHENG Yang

Cite this article:

LI Xiu-ming,JI Jia-fen,LIU Chang-yun, et al. Study on the effects of metabolic syndrome during pregnancy on maternal and infantile lipid metabolism[J]. 中国当代医药, 2018, 25(17): 87-89.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I17/87

[6]	牛建民，雷琼，吕莉娟，等.妊娠期代谢综合征诊断标准的评价[J].中华妇产科杂志，2013，48（2）：1490-1491.
[7]	王伟，杜鹃.妊娠晚期生理性血脂升高的研究[J].中国妇幼保健，2013，28（21）：3422-3423.
[8]	吕艳红杜鹃.妊娠期代谢综合征脂蛋白相关磷脂酶A2变化研究[J]中国实用妇科与产科杂志，2014，30（10）：799-801.
[1]	单梓梅.维、汉老年男性代谢综合征患者骨代谢相关因素分析[J].西部中医药，2017，30（8）：56-59.
[3]	贾伟平.对代谢综合征的探索和研究在继续[J].中华内分泌代谢杂志，2010，26（2）：737-739.
[2]	Zhu XY，Zhang ML，Hou XH，et al.Cigarette smoking increases risk for incident metabolic syndrome in chinesemen-shanghai diabetes study[J].Biomed Environ Sci，2011，24（5）：475-482.
[4]	Bartha JL，Gonzalez-BugattoF，Fernandez-MaciasR，etal.Metabolic syndrome in normal and complicated pregnacies[J].Eur J Obstet Gynecol Reprod Biol，2008，137（2）：178-184.
[5]	Wiznitzer A，Mayer A，Novaek V，et al.Association of lipid levels during gestation with preeclampsia and gestational diabetes metllitus：a population-based study[J].Am J Obstet Gynecol，2009，201（5）：482.el-8.
[9]	EckleRH，GrundySM，ZimmetPZ.Themetabolism syndrome[J].Lancet，2005，365（9468）：1415-1428.
[10]	吴桂贤，吴兆苏，刘静，等.11省市代谢综合征患者中心脑血管病发病率队列研究[J].中华流行病学杂志，2003，24（7）：551-553.
[11]	陈德喜，吕家爱.代谢综合征及其影响因素研究进展[J].实用预防医学，2017，24（9）：1148-1152.
[12]	霍亭竹，罗小丽，毛萌.妊娠期糖尿病对子代健康的影响代谢综合征的传递[J].中国儿童保健杂志，2017，25（7）：687-691.