|
|
|
| Effect of percutaneous nephrostomy in the treatment of upper urinary calculi complicated with urinary sepsis |
| CHEN Jing-ru LIAO Zheng-quan CHEN Jun-wu |
| Department of Urology,the First People′s Hospital of Yidu,Hubei Province,Yidu 443300,China |
|
|
|
|
Abstract Objective To explore the clinical effect of percutaneous nephrostomy in the treatment of upper urinary calculi complicated with urinary sepsis.Methods A total of 80 cases of patients with upper urinary calculi complicated with urinary sepsis from May 2018 to May 2020 in the First People′s Hospital of Yidu were selected as research objects and divided into two groups according to the random number table method,40 cases in each group.The observation group was treated with percutaneous nephrostomy,and the control group was treated with ureteral stent implantation.Then the changes of serum endotoxin level were compared between the two groups before and after treatment.The levels of inflammatory factors before and 3 days after treatment were recorded.The time of body temperature recovery,time of leukocyte recovery and hospitalization time were observed and the incidence of complications was counted in the two groups.Results At 1 and 3 days after treatment,the levels of serum endotoxin in the observation group were lower than those in the control group,the differences were statistically significant (P<0.05).At 3 days after treatment,the levels of tumor necrosis factor-α (TNF-α) and high sensitivity C-reactive protein (hs-CRP) in the observation group were lower than those in the control group,and the differences were statistically significant (P<0.05).The time of body temperature recovery,time of leukocyte recovery and hospitalization time in the observation group were shorter than those in the control group,and the differences were statistically significant (P<0.05).The total incidence of hematoma at the puncture site,renal failure and catheter obstruction in the observation group was lower than that in the control group,and the difference was statistically significant (P<0.05).Conclusion Percutaneous nephrostomy for patients with upper urinary calculi complicated with urinary sepsis can effectively reduce endotoxin level,control inflammatory reaction and shorten hospitalization time,so it has few complications and high safety.
|
|
|
|
|
|
| [1] |
钱永，杜永强，单卫民，等.经皮肾镜、输尿管镜碎石术后尿源性脓毒血症发生的相关危险因素分析[J].国际泌尿系统杂志，2020，40（4）：646-649.
|
| [2] |
邹雄，陈仙，唐亚纯，等.硫化氢对尿源性脓毒血症肾细胞凋亡的影响及其机制[J].医学研究生学报，2020，33（7）：702-707.
|
| [3] |
周欢，雷志培，陈结能，等.双J 管内引流术治疗非手术尿源性脓毒血症的疗效分析[J].深圳中西医结合杂志，2020，30（13）：133-134.
|
| [4] |
杨旭凯，谭乐明，杨成，等.不同严重程度尿源性脓毒血症患者炎性指标变化及其临床意义[J].中华创伤杂志，2020，36（6）：544-549.
|
| [5] |
邹雄，陈悟文，廖国涛，等.输尿管软镜碎石术后尿源性脓毒血症的防治[J].中华腔镜泌尿外科杂志（电子版），2020，14（3）：238-240.
|
| [6] |
秦国东，于文春，邱明，等.经皮肾镜术前及术后监测降钙素原对感染的早期诊断及尿源性脓毒血症预防的临床意义[J].国际泌尿系统杂志，2020，40（3）：419-422.
|
| [7] |
齐士勇，王琦，王兴羽，等.两种肾盂减压方式治疗上尿路结石合并尿源性脓毒血症的效果比较[J].中华泌尿外科杂志，2020，41（4）：256-261.
|
| [8] |
窦全亮，阿不都克力木·阿不都沙塔尔.不同血糖水平的尿源性脓毒血症患者临床特征分析[J].国际泌尿系统杂志，2020，40（2）：309-312.
|
| [9] |
洪含霞，刘梅.英国国家早期预警评分在上尿路结石腔内碎石术后患者中的应用[J].重庆医学，2020，49（5）：773-776.
|
| [10] |
任晓磊，夏海波.泌尿系结石腔镜手术后尿源性脓毒血症发生的原因及防治[J].中华腔镜泌尿外科杂志（电子版），2018，12（5）：356-358.
|
| [11] |
吴佳成，徐海飞，陈志刚，等.经皮肾镜取石术所致尿源性脓毒血症的预测因子临床分析[J].国际泌尿系统杂志，2020，40（1）：89-93.
|
| [12] |
唐玮欣，黄星华，刘雷，等.C反应蛋白、降钙素原与急性生理和慢性健康状况Ⅱ评分对上尿路结石合并尿源性脓毒血症的应用价值[J].国际泌尿系统杂志，2020，40（1）：94-96.
|
| [13] |
谢晓强，杨恩明，杨水法，等.应用中心静脉导管行经皮肾造瘘与经尿道输尿管镜置管在尿源性脓毒血症紧急解压治疗中的疗效比较[J].国际泌尿系统杂志，2019，39（6）：1027-1031.
|
| [14] |
唐亚纯，许武军，陈仙，等，符浩.H2S 通过调控iNOS/HO-1/Bax/Caspase3轴对尿源性脓毒血症所致急性肾损伤的保护作用研究[J].中国免疫学杂志，2019，35（20）：2433-2437，2445.
|
| [15] |
朱澄村，程帆，宁金卓.尿源性脓毒血症相关危险因素的研究进展[J].广西医学，2019，41（13）：1701-1703.
|
| [16] |
沈悦凡，李辉，姚自翔，等.尿肝素结合蛋白在尿源性脓毒血症中的诊断价值[J].浙江医学，2019，41（13）：1428-1430.
|
| [17] |
覃永佳.经皮肾镜及输尿管软镜治疗肾结石术后发生尿源性脓毒血症的对比研究[J].广东医学，2019，40（S1）：163-166.
|
| [18] |
邓廷志.腔内碎石术后尿源性脓毒症早期干预价值的研究[J].实用医技杂志，2019，26（4）：492-494.
|
|
|
|
