Objective To investigate the effects of manual reduction and surgical reduction on patients with distal radius fracture.Methods A total of 84 patients with distal radius fracture admitted to Mudanjiang Forestry Central Hospital from October 2018 to September 2019 were selected as the research objects.According to the random number table method,the patients were divided into manual reduction group (42 cases) and surgical reduction group (42 cases).Patients in the manipulative reduction group received manipulative reduction therapy,while patients in the surgical reduction group received surgical reduction therapy.Operation time,operation cost,fracture healing time,the total incidence of complications rate,wrist range of motion and pain were compared between the two groups.Results After treatment,wrist range of motion score of two groups was higher than that before treatment,and pain score was lower than that before treatment,the differences were statistically significant (P<0.05).The operative time of the surgical reduction group was longer than that of the manual reduction group,the operation cost was higher than that of the manual reduction group,and the fracture healing time was shorter than that of the manual reduction group,the total incidence of complications rate was lower than that of the manual reduction group,the wrist range of motion score was higher than that of the manual reduction group,and the pain score was lower than that of the manual reduction group,the differences were statistically significant (P<0.05).Conclusion In patients with distal radius fractures,surgical reduction is more effective and pain scores are lower.