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Effect of Taiji Yunshou on gastrointestinal function in patients with chronic fatigue syndrome based on brain-gut axis theory |
CHEN Hui1,2 CAI Lian-huan1▲ HE Wei-xiu1 |
1. The First Department of Massage, Rehabilitation Hospital Affiliated to Fujian University of Traditional Chinese Medicine
2. Fujian Provincial Rehabilitation Industrial Institution |
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Abstract Objective To investigate the effect of Taiji Yunshou on gastrointestinal function of patients with chronic fatigue syndrome (CFS) based on brain-gut axis theory. Methods A total of 72 CFS patients admitted to the Rehabilitation Hospital Affiliated to Fujian University of Traditional Chinese Medicine from July 2019 to September 2020 were selected as the research objects, and were divided into control group (36 cases) and experimental group (36 cases)according to the random number table method. The control group received conventional treatment, and the experimental group was treated with Taiji Yunshou on the basis of the control group. The changes of quality of life, fatigue degree,Bristol stool traits, plasma 5-hydroxytryptophan (5-HT), neuropeptide Y (NPY), serum substance P (SP) and calcitonin gene-related peptide (CGRP) were compared between the two groups. Results After treatment, the quality of life scores of the two groups were higher than those before treatment, the fatigue scores of the two groups were lower than those before treatment and the fatigue score of the experimental group was higher than the control group, and the fatigue score was lower than the control group, the differences were statistically significant (P<0.05). After treatment, the good rate of stool traits in the experimental group was higher than that in the control group, and the difference was statistically significant (P<0.05). After treatment, the levels of 5-HT, NPY, SP and CGRP in the two groups were lower than before, and the levels of 5-HT, NPY, SP and CGRP in the experimental group were lower than those in the control group, the differences were statistically significant (P<0.05). Conclusion Taiji yunshou has a better effect on gastrointestinal function of CFS patients, which is better than conventional therapy alone, and has a regulatory effect on 5-HT,NPY, SP, CGRP.
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[1] |
Slomko J,Newton JL,Kujawski S,et al.Prevalence and characteristics of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME)in Poland:a cross-sectional study[J].BMJ Open,2019,9(3):e023955.
|
[2] |
Worm -Smeitink M,Monden R,Groen RN,et al.Towards personalized assessment of fatigue perpetuating factors in patients with chronic fatigue syndrome using ecological momentary assessment:A pilot study[J].J Psychosom Res,2021,140:110296.
|
[3] |
伍侨,高静,柏丁兮,等.中国人群慢性疲劳综合征患病率的Meta 分析[J].右江医学,2020,48(10):13-21.
|
[4] |
边红恩,陈团营,单海军.重灸疗法对心脾两虚型慢性疲劳综合征患者临床疗效的研究[J].中医药信息,2021,38(3):65-68.
|
[5] |
钱立锋,姚青,朱高峰.经筋推拿配合易筋经功法锻炼在慢性疲劳综合征睡眠障碍中的研究[J].中华全科医学,2016,14(11):1886-1888,1951.
|
[6] |
刘琴,周薇,钟心媛,等.功法治疗慢性疲劳综合征的Meta分析[J].中医药导报,2020,26(6):67-73,79.
|
[7] |
朱凤亚,江泰君,汤莉洁,等.针灸治疗慢性疲劳综合征肠道菌群-免疫功能的作用机制[J].中国中医基础医学杂志,26(9):1354-1358.
|
[8] |
Armstrong CW,McGregor NR,Lewis DP,et al.Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients[J].Metabolomics,2015,11(6):1626-1639.
|
[9] |
Fukaka K,Stvaus SE,Hicki E,et al.The chvonie,Fatigue,Syndvome,A compvehensive approach to its definition and stuag Inlevenational chvonie Fatigue Syndvome stadg Gvoap[J].Ann Inter Med,1994,121(12):953-959.
|
[10] |
胡祖应,胡香春,朱嫒嫒,等.SF-36 量表在职业病患者生存质量调查中的应用[J].中华劳动卫生职业病杂志,2020,38(11):846-848.
|
[11] |
季英霞.吐纳法联合穴位贴敷预防中老年髋部骨折卧床后便秘的护理研究[D].北京:中国中医科学院,2017.
|
[12] |
孙增坤,蒙玲莲,何裕民.从“重启慢性疲劳综合征研究”受关注谈起[J].科学通报,2019(23):2379-2385.
|
[13] |
李蓉,张斌,任天顺,等.太极拳运动对糖尿病辅助治疗作用的研究进展[J].中国当代医药,2018,25(24):33-36.
|
[14] |
周肸,钱海华,张丹,等.基于肠道菌群与脑肠轴的相互作用机理探讨中医脑肠学说[J].中华中医药学刊,2020,38(3):127-130.
|
[15] |
EJ Lim,Son CG.Review of case definitions for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)[J].J Trans Med,2020,18(1):2-10.
|
[16] |
张敬苑,兰益,袁秀丽.基于脑肠轴学说探讨头针治疗胃肠疾病的思路[J].云南中医中药杂志,2019,40(10):83-85.
|
[17] |
Tait C,Sayuk GS.The Brain-Gut-Microbiotal Axis:A framework for understanding functional GI illness and their therapeutic interventions[J].Eur J Intern Med,2021,84(7):1-9.
|
[18] |
张超,李江宁,郭宏铭.功能性下颌偏斜大鼠三叉颈核内炎症相关细胞因子和痛觉传递相关神经递质含量变化研究[J].北京口腔医学,2018(3):26-29.
|
[19] |
Lee Y,Kim YK.Understanding the Connection Between the Gut-Brain Axis and Stress/Anxiety Disorders[J].Curr Psychiat Rep,2021,23(5):22.
|
|
|
|