|
|
Analysis of the influencing factors of quality of life in patients with chronic hepatitis C |
ZHU Ren-ying1 ZHAO Yu-mei2 LI Yue3▲ WANG Li-li1 AN Yun-feng4 HUANG Shuang-li5 |
1.Department of Nursing, Hongqi Hospital Affiliated to Mudanjiang Medical College, Heilongjiang Province, Mudanjiang 157000, China;
2.Department of Pharmacy, Hongqi Hospital Affiliated to Mudanjiang Medical College, Heilongjiang Province, Mudanjiang 157000, China;
3.Department of Nephrology, Hongqi Hospital Affiliated to Mudanjiang Medical College, Heilongjiang Province, Mudanjiang 157000, China;
4.Department of Medical, Hongqi Hospital Affiliated to Mudanjiang Medical College, Heilongjiang Province, Mudanjiang 157000, China;
5.School of Nursing,Hongqi Hospital Affiliated to Mudanjiang Medical College, Heilongjiang Province, Mudanjiang 157000, China |
|
|
Abstract Objective To analyze the influencing factors of quality of life in patients with chronic hepatitis C in order to provide references for the optimization of treatment regimens.Methods A total of 536 patients with chronic hepatitis C (including 7 cases of shedding) in Hongqi hospital Affiliated to Mudanjiang Medical College from January 2016 to December 2017 were selected as the research objects.All patients were treated with the same antiviral regimen.Before and after treatment, the quality of life of the patients was evaluated by using the health status survey, and the data such as gender and educational level of the patients were investigated and collected to analyze the influencing factors.Results The results of univariate analysis indicated that there were statistically significant differences in the education level, monthly economic income, hobbies, marital status and residence status between the group with good quality of life and the group with poor quality of life (P<0.05).The results of Logistic multivariate analysis indicate that education level (β=2.372, OR=12.125, 95%CI 5.125-33.256), monthly economic income (β=1.050, OR=2.851, 95%CI 1.358-7.226), hobbies (β=2.376, OR=14.265, 95%CI 4.568-31.265), marital status (β=2.595, OR=15.233, 95%CI 4.215-30.235) and living conditions (β=2.602, OR=15.389, 95%CI 4.189-33.358) were related factors affecting the quality of life of patients with chronic hepatitis C (P<0.05).Conclusion The factors influencing the quality of life of patients with hepatitis C are complex, mainly including education level, monthly economic income, hobbies, marital status and living conditions, etc.It is suggested that doctors should pay attention to the above factors to further improve the rehabilitation effect of patients.
|
|
|
|
|
[1] |
黄妩姣.丙型肝炎患者血清肝功能与肝纤维化的相关性[J].广东医学,2010,31(24):3218-3219.
|
[2] |
庄小芳.3 种无创诊断技术对慢性乙型肝炎肝纤维化的评估价值比较[J].临床肝胆病杂志,2016,32(8):1508-1512.
|
[3] |
刘文俊.肝功能指标与丙型肝炎的相关性研究进展[J].中国临床新医学,2018,11(9):957-958.
|
[4] |
赵巍巍.聚乙二醇干扰素联合利巴韦林治疗慢性丙型肝炎患者的疗效及影响因素分析[J].当代医学,2019,25(5):156-157.
|
[5] |
中华医学会肝病学分会,中华医学会感染病学分会.丙型肝炎防治指南(2015年更新版)[J].中国病毒病杂志,2015,5(6):425-426.
|
[6] |
金虹.皖东地区老年人群生存质量及影响因素[J].滁州职业技术学院学报2018,17(3),47-51.
|
[7] |
张磊.SF-36 量表中文版的应用及分级截断点选择的研究[J].中华流行病学杂志,2004,25(1):69-73.
|
[8] |
刘文俊.丙型肝炎患者RNA 载量和肝功能指标及血细胞参数的相关性分析[J].中国临床新医学,2017,10(12),1168-1171.
|
[9] |
靳镝.重组人干扰素α2a 联合利巴韦林治疗慢性丙型肝炎合并脂肪肝的效果[J].中国当代医药2018,25(33),59-61.
|
[10] |
廖常斌.乌鲁木齐慢性丙型肝炎合并非酒精性脂肪肝的危险因素[J].中国当代医药,2016,23(7):18-20.
|
[11] |
唐芬.聚乙二醇干扰素联合利巴韦林治疗慢性丙型肝炎疗效观察及影响因素分析[J].陕西医学杂志,2016,45(7):894-896.
|
[12] |
王善昌.聚乙二醇干扰素联合利巴韦林治疗慢性丙型肝炎的疗效及疗效影响因素分析[J].医药论坛杂志,2015,36(1):150-153.
|
[13] |
蒋秀琳,王明华,李玲,等.派罗欣联合抗病毒治疗对慢性丙肝病人病毒RNA 定量、肝功能及Th1/Treg 细胞因子含量的影响[J].医学动物防制,2019,35(8):796-799,802.
|
[14] |
王超杰.利巴韦林联合聚乙二醇干扰素α-2a 治疗慢性丙肝的疗效与安全性探究[J].现代诊断与治疗,2017,28(15):2788-2789.
|
[15] |
程琳.聚乙二醇干扰素治疗慢性丙肝患者的临床疗效及不良反应探讨[J].基层医学论坛,2019,23(2):216-217.
|
|
|
|