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| Effect comparison of different methods in the treatment of ovarian cancer and their impact on patients′ quality of life |
| LAI Ying |
| Department of Gynecology,Luoding People′s Hospital of Guangdong Province,Luoding 527200,China |
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Abstract Objective To compare the effect of different methods in the treatment of ovarian cancer and their impact on patients′ quality of life.Methods A total of 58 patients with ovarian cancer from January 2015 to Octorber 2017 were selected as the subjects,and divided as the experimental group and control group by random number table method,with 29 cases in each group.The experimental group was treated with preopearative Paclitaxel+Carboplatin (TC)chemotherapy+cytoreductive surgery+peritoneal TC thermofusion+postoperative conventional chemotherapy,and the control group recerived cytoreductive surgery+postoperative routine chemotherapy.The operation condition,treatment effect,quality of life score,complications,recurrence rate and mortality of the two groups were compared.Results The operation time and hospitalization time of the experimental group were shorter than those in the control group,and the differences were statistically significant (P<0.05).The amount of blood loss ([425.29±142.73] ml) and ascites([670.35±163.87] ml) in the experimental group were less than those in the control group ([801.62±125.26],[893.40±164.38] ml),and the differences were statistically significant (P<0.05).The total effective rate of the experimental group was higher than that of the control group,and the difference was statistically significant (P<0.05).There was no significant difference in the quality of life scores between the two groups before treatment (P>0.05).The scores of emotional function and total health status in the experimental group were higher than those before treatment and the control group,while the scores of pain,fatigue,constipation and shortness of breath in the experimental group were lower than those before treatment and the control group,and the differences were statistically significant (P<0.05).The scores of pain and fatigue in the control group were lower than before treatment,and the differences were statistically significant(P<0.05).There was no significant difference in the incidence of complications between the two groups (P>0.05).The recurrence rate and mortality rate of the experimental group were lower than those of the control group,and the differences were statistically significant (P<0.05).Conclusion For patients with ovarian cancer,preopearative TC chemotherapy+cytoreductive surgery+peritoneal TC thermofusion+postoperative conventional chemotherapy has better curative effect than tumor cytoreductive surgery+postoperative conventional chemotherapy,which can be widely used in clinic.
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