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Effect of intervention in the second and third trimester of gestational diabetes mellitus on the outcome of mother and infant |
WU Sha LIU Ke-ling FU Qing-mei |
Department of Obstetrics, Bao′an District People′s Hospital of Shenzhen City, Guangdong Province, Shenzhen 518101, China |
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Abstract Objective To explore the effect of intervention in the second and third trimester of gestational diabetes mellitus (GDM) on the outcome of mother and infant. Methods From July 1, 2017 to June 1, 2019, 600 patients with gestational diabetes were enrolled in our hospital.According to the gestational group, the second trimester group (28-32 weeks, 300 cases) and the third trimester group (>32 weeks, 300 cases) took targeted interventions and followed up the patients to production.The complications, neonatal complications, Apgar score and delivery mode were compared between the two groups. Results The total incidence of complications in the intervention period of patients in the second trimester group was 14.00%, lower than 41.00% in the third trimester group, the total incidence of neonatal complications in the second trimester group was 3.33%, the conversion rate was 5.00%, lower than 23.00% and 20.00% in the third trimester group, and the Apgar score of newborns in the second trimester group was higher than that in the third trimester group, the natural delivery rate of patients in the second trimester group was 60.00%, higher than that in the third trimester group, the differences were statistically significant (P<0.001). Conclusion Health education, diet, medication and other interventions in the second trimester of pregnancy can significantly reduce the complications after intervention, improve the outcome of mother and infant, improve the natural delivery rate and Apgar score of newborn,and reduce the rate of neonatal transfer.The effect is ideal.
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[1] |
戴亚娟.妊娠期糖尿病对妊娠结局的影响[J].现代医药卫生,2016,32(22):3503-3505.
|
[2] |
谢幸,孔北华,段涛.妇产科学[M].北京:人民卫生出版社,2018:105-107.
|
[3] |
张丽伟.妊娠期糖尿病综合干预治疗对妊娠结局的影响[J].中国现代药物应用,2016,10(21):197-198.
|
[4] |
王影,刘伟,王景,等.门冬胰岛素联合生物合成人胰岛素治疗妊娠期糖尿病临床观察[J].解放军医药杂志,2016,28(1):96-100.
|
[5] |
秦凤云.妊娠期糖尿病及其相关因素对新生儿体脂含量的影响研究[D].合肥:安徽医科大学,2016.
|
[6] |
郭慧洁,徐倩倩,王吉平.妊娠期糖尿病发病的相关因素分析和护理对策[J].护理研究,2016,30(15):1827-1831.
|
[7] |
莫育霞,廖化梅,周燕.妊娠期糖尿病与脂肪因子参与的胰岛素抵抗的相关性研究进展[J].现代医药卫生,2017,33(18):2810-2812.
|
[8] |
刘洋,张佳琦,唐淑洁.门冬胰岛素与生物合成人胰岛素治疗妊娠期糖尿病的疗效比较[J].中国医院用药评价与分析,2016,16(10):1331-1333.
|
[9] |
罗琳雪,李雪静,陈丽芬,等.产科教育门诊个性化的健康教育对妊娠期糖尿病妊娠结局影响的研究[J].中国妇幼保健,2016,31(17):3449-3451.
|
[10] |
李利平,姜宏卫,刘婕,等.维生素D 与妊娠糖尿病相关性的临床研究[J].中国医师杂志,2016,18(3):434-435.
|
[11] |
谭志华,任为,成晓霞.妊娠期糖尿病分娩期管理对妊娠结局的影响[J].公共卫生与预防医学,2015,26(4):114-115.
|
[12] |
袁妙兰,李意,冯慧芳,等.妊娠期糖尿病危险因素研究及对妊娠结局的影响[J].中国医师杂志,2017,19(10):90.
|
[13] |
Aksan G,Gedikli O,Keskin K,et al.Is galectin-3 a biomarker,a player-or both-in the presence of coronaryatherosclerosis?[J].J Investig Med,2016,64(3):764-770.
|
[14] |
Gonzalez GE,Rhaleb NE,D′Ambrosio MA,et al.Cardiacdeleterious role of galectin-3 in chronic angiotensin Ⅱ-induced hypertension[J].Am J Physiol Heart Circ Physiol,2016,311(5):H1287-H1296.
|
[15] |
景小凡,柳园,饶志勇,等.妊娠期糖尿病对母婴结局影响分析[J].华西医学,2016,31(2):301-305.
|
[16] |
杨秋霞,方倩.胰岛素泵短期强化干预联合生物合成人胰岛素治疗妊娠期糖尿病的临床疗效及对母婴结局的影响[J].中国生化药物杂志,2016,36(9):135-137.
|
[17] |
孙艳秋,吴振兰,孙婧,等.不同妊娠期孕妇血清维生素A、维生素E、铁、钙含量分析[J].潍坊医学院学报,2016,38(6):433-435.
|
[18] |
张硕,宋薇薇.妊娠期糖尿病产妇分娩巨大儿相关因素分析[J].中国生育健康杂志,2016,27(3):215-218.
|
[19] |
Imran TF,Shin HJ,Mathenge N,et al.Meta-analysis of the usefulness of plasma galectin-3 to predict the risk of mortality in patients with heart failure and in the general population[J].AmJ Cardiol,2017,119(1):57-64.
|
|
|
|