|
|
Correlation study of calcification factors in radial artery in uremia patients |
MO Yi-hao1 SONG Dai-kun1 KANG Wen-hui2 WANG Li1 HU Ming-liang1 |
1.Department of Nephrology,People′s Hospital in Longhua District of Shenzhen City,Guangdong Province,Shenzhen 518109,China;
2.Department of Cardiac Sonography,People′s Hospital in Longhua District of Shenzhen City,Guangdong Province,Shenzhen 518109,China |
|
|
Abstract Objective To investigate the correlation of calcification factors of radial artery in uremia patients.Methods From January 2015 to December 2016,60 cases of uremic patients treated in our hospital were selected as the research objects.The von Kossa staining for radial artery blood vessel,and X-ray film for both hands and pelvis was photographed.The vascular calcification score was calculated,blood pressure indexes were measured,blood biochemical indexes such as phosphorus and calcium were detected,and the level of whole parathyroid hormone was detected,and the correlation of vascular calcification was analyzed.Results In this study,a total of 29 patients developed radial artery calcification,accounted for 48.33%.The serum phosphorus,calcium phosphate product,alkaline phosphatase,parathyroid hormone,vascular calcification rate and vascular calcification score of the patients with radial artery calcification were all higher than those patients without radial artery calcification,and the differences were statistically significant(P<0.05).There was no significant difference in age,gender,serum total calcium and serum creatinine between patients with and without radial artery calcification (P>0.05).Vascular calcification was taken as the dependent variable,and the results of multiple linear regression suggested that there were positive correlation between high level of serum phosphorus,total parathyroid hormone vascular calcification rate,alkaline phosphatase calcium phosphate product and the formation of vascular calcification (r=0.503,0.281,0.519,0.542,0.451,P<0.05).Conclusion Calcification of the radial artery is common in uremic patients,and there is a significant correlation between serum phosphorus,vascular calcification rate,alkaline phosphatase and calcium phosphorus product and the formation of calcification of the radial artery in uremic patients.
|
|
|
|
|
[14] |
Teng LB,Chang M,Liu SX,et al.Peritonealmicrovascular endothelial function and the microinflammatory state are associated with baseline peritoneal transport characteristics in uremic patients[J].Int Urol Nephrol,2015,47(1):191-199.
|
[15] |
冯闯丽,陈金玲,宋宏宁,等.舒张期应变率参数评价尿毒症患者左心室舒张功能[J].中华超声影像学杂志,2017,26(12):1018-1023.
|
[1] |
刘静静,任伟,王科,等.糖尿病肾病尿毒症患者成纤维细胞生长因子23和骨保护素与桡动脉血管钙化的相关性[J].中国临床保健杂志,2016,19(2):177-180,227.
|
[2] |
莫怡浩,宋代坤,康文慧,等.尿毒症患者血清钙化相关蛋白与血管钙化的关系研究[J].山西医药杂志,2017,46(22):2696-2699.
|
[3] |
梁虹,高海娥,李飞,等.糖尿病肾病尿毒症患者尿路感染危险因素分析与预防[J].中华医院感染学杂志,2016,26(5):1056-1058.
|
[4] |
黄柳,黄燕林,郭阳化,等.尿毒症腹膜透析患者疾病不确定感及影响因素研究[J].护理管理杂志,2015,15(1):29-31.
|
[5] |
王莉华,侯晶晶,高永宁,等.Treg/Th17细胞失衡对尿毒症血液透析患者微炎症因子及血管钙化的影响[J].中国老年学杂志,2016,36(22):5691-5693.
|
[6] |
胡闪闪,杨宁,孙喜霞,等.尿毒症患者冠状动脉钙化与血压变异性的相关性研究[J].中国现代医学杂志,2017,27(27):64-70.
|
[7] |
胡诗德,简讯,陈慧,等.血液透析滤过与高通量血液透析对尿毒症患者血管钙化的影响[J].临床肾脏病杂志,2017,17(9):553-556,577.
|
[8] |
李杨,孙文,周伟,等.通淋汤对尿毒症患者血管钙化因子BMP-2,OPG表达的影响[J].现代中西医结合杂志,2017,26(18):1959-1961,1965.
|
[9] |
于永利.通淋汤对尿毒症患者骨形态发生蛋白-2表达的影响研究[J].检验医学与临床,2016,13(7):938-939.
|
[10] |
王明波,谭永顺,王自良,等.血液透析对尿毒症患者Treg与 Th17 水平失衡的影响分析[J].重庆医学,2018,47(15):2045-2047.
|
[11] |
Makidon,Paul ES, Douglas M,et al.Effect of chronic uremia on the cell surface expression of B7 family costimulatory moleculesinan HLA-A2transgenic mouse model of chronic kidney disease[J].Comp Med,2015,65(4):308-314.
|
[12] |
叶爱玲,刘君,陈惠琳,等.高通量血液透析在治疗尿毒症患者中的应用[J].护理实践与研究,2015,12(4):24-26.
|
[13] |
侯爱珍,陈囿元,肖观清,等.尿毒症维持性血液透析患者的死亡原因[J].实用医学杂志,2016,32(2):283-285.
|
|
|
|