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Study on the current status of HPV infection and age stratification in 2915 women |
XU Wen-jin1 OU Feng-rong2▲ WANG Hong1 ZHOU Xiao-li1 YAN Hua1 |
1.Institute of Family Planning Science of Liaoning Province,Shenyang 110031,China;2.School of Public Health of China Medical University,Liaoning Province,Shenyang 110001,China |
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Abstract Objective To analyze the the current status of human papilloma virus(HPV)infection and age stratification in 2915 women to provide the theoretical basis for the prevention and treatment of cervical cancer.Methods Cervical exfoliative cells and detection results in 2915 women voluntarily carrying out HPV infection test from January 2016 to July 2017 were collected.HPV typing was tested using fluorescence PCR technology,and 15 types of HPV subtypes could be detected.Results The positive rate of HPV was 22.23%(648/2915).They were divided into the 4 age groups(<30 years old,30-39 years old,40-49 years old,and≥50 years old)to carry out analysis.The HPV positive rate of the 4 groups was different,and the age group(≥50 years old)was the highest,and there was a significant difference between the ≥50 years old group and the other 3 groups respectively(χ2=3.94,6.21,4.34,P<0.05).Age stratification analysis showed that the positive rate of HPV in each age group was"U"curve.Among 15 HPV subtypes of infection detected,the top 2 was HPV18,16 respectively,and the positive rate of HPV in HPV18 and 16 was higher in<30 years old and≥50 years old.Conclusion Female HPV infection is related to age stratification.Young women,perimenopausal women and above-mentioned women need to be highly alert to the risk of HPV infection.
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[1] |
Castellsagué X,Bosch FX,Munoz N.Envirnmental co-factors in HPV carcinogensis[J].Virus Res,2002,89(2):191-199.
|
[2] |
魏丽惠.HPV感染现状及在宫颈癌和癌前病变筛查中的意义[J].实用妇产科杂志,2017,33(2):81-83.
|
[3] |
Zhao FH,Lin MJ,Chen F,et al.Performance of high-risk human papillomavirus DNA testing as a primary screen for cervical cancer:a pooled analysis of individual patient data from 17 population-based studies from China[J].Lancet Oncol,2010,11(12):1160-1171.
|
[4] |
聂小毳,史玉林,丛建萍,等.宫颈上皮内瘤变锥切术切缘阳性相关因素分析[J].中华肿瘤防治杂志,2016,23(4):262-265.
|
[5] |
张立娟,武佳蕾,孙树荣.北京市北苑地区女性HPV感染现状及基因型分布研究[J].标记免疫分析与临床,2016,23(1):15-18.
|
[6] |
陈芬,蔡德正,陈派生.宁德地区HPV联合TCT检测在宫颈癌前病变及宫颈癌筛查中的价值研究[J].中国实用医药,2016,11(3):101-102.
|
[7] |
谢成耀,安舒,韩阳,等.辽沈地区23760例妇科就诊患者HPV 感染状况分析[J].中国卫生统计,2014,31(2):268-269.
|
[8] |
聂妹芳,李登清,黄民主,等.11461例妇科门诊患者HPV亚型感染状况的研究[J].中国现代医学杂志,2011,21(27):3434-3438.
|
[9] |
鄢春晖,陈林,袁蔓莉,等.重庆地区12196例妇科门诊患者 HPV 亚型感染情况分析[J].重庆医学 2014,43(35):48-50.
|
[10] |
谢幸,苟文丽.妇产科学[M].8版.北京:人民卫生出版,2013.
|
[11] |
曹清香,高红,唐清,等.衡阳地区女性感染21种型别人乳头瘤病毒现状分析[J].国际检验医学杂志,2014,35(14):1830-1832.
|
[12] |
于海聪,李佩玲,王红丽.哈尔滨地区HPV感染现状与年龄的分层分布[J].现代肿瘤医学,2016,24(19):3104-3107.
|
[13] |
李红.液基细胞学和HPV-DNA检测在宫颈癌及癌前病变筛查中的价值研究[J].现代实用医学,2013,25(10):1143-1144.
|
[14] |
林志金,曾宪瑞,王晓波,等.宫颈液基细胞学检查联合HPVDNA检测在宫颈癌筛查中的应用[J].江西医药,2016,51(5):477-478,486.
|
[15] |
Huh WK,Ault KA,Chelmow D,et al.Use of primary highrisk human papilloma virus testing for cervical cancer screening:interim clinical guidance[J].Gynecol Oncol,2015,136(2):178-182.
|
|
|
|