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| The influence of Trimetazadine on the clinical efficacy of patients with chronic heart failure |
| ZHANG Bo |
| The First Department of Internal Medicine,Traditional Chinese Medicine Hospital of Meizhou City in Guangdong Province,Meizhou 514071,China |
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Abstract ObjectiveTo evaluate the effects of Trimetazadine on patients with chronic heart failure.Methods100 patients with chronic heart failure treated in our hospital form February 2016 to February 2017 were selected as the subjects,and divided into therapy group and control group,50 cases in each group.The control group patients were given basic treatment with angiotensin converting enzyme inhibitor(ACEI),digitalis,diuretics,βblock.And the therapy group were given Trimetazadine in addition to the basic treatment.Heart function,LVEF,LVDD,LVDS and BNP level in those patients were observed before and after three months treatment.ResultsCompared with the control group,the total effective rate increased significantly in the therapy group.After treatment,the LVEF of the patients was obviously improved,and RHR in therapy group was decreased.LVDD,LVDS and BNP level also decreased at 3 months compared with those in therapy group,the difference was statistically significant(P＜0.05).ConclusionIn additional to the conventional therapy,Trimetazadine can improve the left ventricular performance and remodeling in patients with coronary heart failure.
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