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Clinical efficacy of Alprostadil sequential therapy in the treatment of elderly patients w ith clinical diabetic nephropathy |
ZENG Zhi-yong YAN Hai-lan HU Yan-hong WANG Yan-hong |
Department of First Internal Medicine,People′s Hospital in Sihui City,Guangdong Province,Sihui 526200,China |
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Abstract ObjectiveTo investigate the clinical efficacy of Alprostadil as a sequential therapy in the treatment of clinical diabetic nephropathy in the elderly.MethodsA total of 200 elderly patients with diabetic nephropathy in clinical stage who were admitted in our hospital from February 2015 to September 2017 were selected as research objects,and randomly divided into routine group and research group,with 100 cases in each group.Routine group was treated with Alprostadil therapy on the basis of routine treatment,while research group was treated with Alprostadil sequential therapy on the basis of routine treatment,and the therapeutic efficacy and renal function indexes changes before and after treatment were compared between the two groups.ResultsThe total effective rate of treatment in the study group was higher than that in the conventional group,and the difference was statistically significant(P<0.05).After treatment,the renal function indexes of the two groups of patients were lower than those before treatment,and the renal function indexes of the patients in the study group were higher than those of the conventional group,the difference was statistically significant(P<0.05).ConclusionOn the basis of routine treatment,application of Alprostadil as a sequential therapy in the treatment of elderly patients with clinical diabetic nephropathy obtains a better clinical effect,which can improve the therapeutic efficacy and significantly ameliorate the patients′various renal function indexes.
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[1] |
王珊珊,常宝成,单春艳,等.前列地尔序贯疗法治疗老年临床糖尿病肾病期患者的疗效观察[J].中华老年医学杂志,2014,33(2):154-158.
|
[2] |
周斌.前列地尔序贯疗法治疗老年临床期糖尿病肾病患者的疗效观察[J].吉林医学,2016,37(8):1989-1990.
|
[3] |
赖小航,杨沛华.探讨前列地尔序贯疗法治疗老年临床期糖尿病肾病的临床效果[J].当代医学,2016,22(7):154-155.
|
[4] |
曹鸿茹.前列地尔序贯疗法治疗老年临床期糖尿病肾病患者的临床效果[J].糖尿病新世界,2016,19(15):22-23.
|
[5] |
黄红梅,吴燕,冉小林,等.探讨前列地尔序贯疗法治疗老年临床期糖尿病肾病患者的疗效[J].中国保健营养,2017,27(2):126-127.
|
[5] |
贺晓莉,雒华.前列地尔与贝前列素钠序贯疗法对老年临床期糖尿病肾病的疗效及安全性评估[J].中国医师进修杂志,2014,37(36):36-38.
|
[6] |
韦娟,吴永秀.前列地尔序贯疗法治疗老年临床期糖尿病肾病患者的临床研究[J].东方食疗与保健,2016,10(9):115.
|
[7] |
崔向勇.探讨前列地尔序贯疗法治疗老年临床期糖尿病肾病患者的疗效[J].临床研究,2015,(11):45-47.
|
[8] |
王珊珊,陈莉明,常宝成,等.前列地尔序贯疗法治疗老年临床糖尿病肾病的研究[C].//中华医学会糖尿病学分会第十七次全国学术会议论文集.2013:247.
|
[9] |
韦建.前列地尔序贯疗法治疗老年临床期糖尿病肾病患者的疗效观察[J].临床医学工程,2016,23(9):1193-1194.
|
[10] |
黄智敏,陈科杰.老年临床期糖尿病肾病患者实施前列地尔序贯疗法治疗的临床效果观察[J].糖尿病新世界,2016,19(19):85-86.
|
[11] |
崔影,陈静.前列地尔序贯疗法治疗老年临床期糖尿病肾病 65 例临床观察[J].社区医学杂志,2017,15(2):70-71.
|
[12] |
赖小航,杨沛华.探讨前列地尔序贯疗法治疗老年临床期糖尿病肾病的临床效果[J].当代医学,2016,22(7):154-155.
|
[13] |
张林霞,孙茜,孙波,等.前列地尔注射液与贝前列素钠片序贯治疗老年糖尿病肾病的疗效[J].中国老年学杂志,2015,11(7):1754-1756.
|
[14] |
贺晓莉,雒华.前列地尔与贝前列素钠序贯疗法对老年临床期糖尿病肾病的疗效及安全性评估[J].中国医师进修杂志,2014,37(36):36-38.
|
[15] |
李桃.前列地尔序贯疗法治疗老年临床期糖尿病肾病62例临床观察[J].社区医学杂志,2017,15(17):58-59.
|
|
|
|