血清降钙素和C-反应蛋白联合检测在新生儿感染性疾病诊断中的价值分析

Abstract
Figure/Table
References (15)
Related Citation (15)

Download: PDF (0 KB) HTML (30 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To study the value of combined detection of calcitonin(PCT)and C-reactive protein(CRP)in the diagnosis of neonatal infectious diseases.Methods Participants 44 newborns(observation group)and 44 normal newborns(control group)admitted to our hospital from March 2016 to April 2017 were enrolled in this study.Infections were collected before treatment 3 ml venous in children with disease and 3 ml venous blood in control group within 7 days after birth.PCT and CRP were measured in two groups.Venous blood before treatment and 10 days after treatment were collected in the observation group,CRP,neutrophil(NEUT)content,using Spearman rank correlation coefficient test PCT,CRP NEUT content correlation.Results The serum levels of PCT and CRP in the two groups were significantly higher than those in the control group (P<0.05).The positive rate of PCT and CRP in the observation group was significantly higher than that in the control group(P<0.05).The levels of PCT,CRP and NEUT in the observation group were significantly lower than those before treatment,the differences were statistically significant(P<0.05).The results of PCT,CRP and NEUT were based on the Spearman rank correlation coefficient.The results showed that PCT,CRP and NEUT were related(P<0.05).Conclusion PCT and CRP haveimportant value in the early diagnosis of neonatal infectious diseases,determine the degree of infection,and determine the therapeutic effect,and apply them to clinical practice.

Key words： PCT CRP NEUT Neonatal Infectious disease Spearman rank correlation coefficient

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	LI Fu
	YANG Xiao-mei
	WU Chun-hong
	WEI Lin-Yan
	LAN Jin-sheng

Cite this article:

LI Fu,YANG Xiao-mei,WU Chun-hong, et al. Analysis of PCT and CRP combined detection in the diagnosis of neonatal infectious diseases[J]. 中国当代医药, 2018, 25(12): 122-124.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I12/122

[13]	曹献云，李岩，剧松丽，等.新生儿感染性休克发生与疾病危重评分和多脏器功能损害的关系研究[J].中华医院感染学杂志，2017，27（2）：425-428.
[14]	王瑞芬，杨悦青，肖敏，等.宫腔内感染新生儿转运至新生儿监护病房过程中耳、咽拭子培养与发生新生儿感染的相关性[J].中国医药导刊，2017，19（5）：448-449.
[1]	王耀华.新生儿感染性疾病患儿降钙素原水平的变化分析[J].中国妇幼保健，2015，30（20）：2021-2022.
[2]	古艳云，马静，杨兰菊，等.目标性感染监测对新生儿感染干预效果研究[J].中华医院感染学杂志，2016，26（5）：1152-1154.
[3]	关小勇，蒋丽华，傅锦坚，等.超敏C反应蛋白检测在新生儿感染性疾病诊疗上的应用误区[J].中国妇幼保健，2016，31（6）：1197-1198.
[4]	张海金，赵玉，程丽萍.新生儿感染病原菌检测及耐药特征研究[J].中国妇幼保健，2015，30（21）：3608-3610.
[5]	曾玲.新生儿感染性休克与新生儿疾病危重病例评分及多脏器功能损害间的关系[J].安徽医药，2016，20（3）：529-530.
[6]	邵民坤，周燕，杜坤，等.炎性指标联合检测在鉴别诊断新生儿感染中的临床评价[J].中华医院感染学杂志，2016，26（7）：1639-1641.
[7]	朱晓洁，王粉，张君平，等.新生儿感染性休克的死亡危险因素分析[J].中华医院感染学杂志，2017，27（9）：2111-2113.
[8]	王利利，席晓莹，姜朕，等.新生儿感染性疾病血小板参数、降钙素原的变化及临床意义[J].浙江医学，2016，8（13）：1116-1118.
[9]	卢圆圆，吴培，姚惠芬，等.降钙素原在鉴别诊断新生儿凝固酶阴性葡萄球菌血流感染与污染的应用价值[J].中国微生态学杂志，2016，28（7）：811-815.
[10]	余霞，王素萍，朱悦萍，等.新生儿重症监护病房医院感染检测结果分析及干预策略[J].中华医院感染学杂志，2017，27（4）：903-906.
[11]	林艳，李微，黄颖璇，等.血清PCT与hs-CRP对新生儿细菌感染性肺炎的诊断价值[J].海南医学，2017，28（10）：1627-1628.
[12]	李桦，王晓蕾，杨涛毅，等.新生儿流感嗜血杆菌感染前瞻性多中心流行病学调查与病例对照研究[J].中国小儿急救医学，2017，24（1）：34-38.
[15]	周素芽，王丽娜，周琴，等.血清降钙素原与超敏C-反应蛋白在新生儿感染性疾病中的表达及其临床评价[J].中华医院感染学杂志，2016，26（12）：2837-2839.