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Clinical evaluation of procalcitonin determination in children with sepsis |
QIN Chao-qiang DING Yong-xing CHEN Juan |
Department of Pediatrics,Yunfu People′s Hospital in Guangdong Province,Yunfu 527300,China |
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Abstract ObjectiveTo explore the clinical sinificance of procalcitonin (PCT)for diagnosis and prognosis of children with sepsis.Methods100 infected children treated in department of pediatrics in our hospital from February 2014 to February 2016 were selected.They were divided into the severe sepsis group (17 cases),non severe sepsis group(23 cases),and non-sepsis group (60 cases)according to the diagnosis criteria.PCT,CRP,WBC were determined and pediatric critical illness score (PICS)was conducted in all cases within 24 hour after admission.ResultsThere was a satatistical difference in PICS,PCT,CRP,WBC among the three groups (P<0.01).The level of PCT,CRP,WBC in the severe sepsis group and non severe sepsis group were higher than those in the non-sepsis group(P<0.01).There was no statistical difference of CRP,PCT level between the severe sepsis group and non severe sepsis group(P>0.05).ConclusionIn the diagnosis of sepsis,PCT is better than CRP and WBC,and it is a sensitive serological indicator.The higher the level of PCT,the lower the PICS.
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[1] |
中华医学会儿科学分会急救学组,中华医学会急诊学分儿科学组,《中华儿科杂志》编辑委员会.儿科感染性休克(脓毒性休克)诊疗推荐方案[J].中华儿科杂志,2006,44(8):596-598.
|
[2] |
中华医学会儿科学分会急救学组,中华医学会急诊学分儿科学组,中国医师协会儿童重症医师分会.儿童脓毒性休克(感染性休克)诊治专家共识(2015版)[J].中华儿科杂志,2015,53(8):576-578.
|
[3] |
张娙,董静莲,王书亮.降钙素原与D-二聚体在评估急诊脓毒症患者病情及预后的研究[J].中华医院感染学杂志,2015,25(1):11-13.
|
[4] |
魏万昆,万程彬,张毅.不同真菌感染对降钙素原的差异与疾病预后的关系[J].中华医院感染学杂志,2015,25(9):1937-1939.
|
[5] |
邓建君,周川,谢萍,等.血清降钙素原与急性心肌梗死患者炎症反应的相关性研究[J].中国循环杂志,2015,30,(4):335-338.
|
[6] |
龙涛,白蓉蓉,李智,等.降钙素原与C-反应蛋白对术后重度脓毒血症患者预后的影响[J].中华医院感染学杂志,2015,25(13):2881-2883.
|
[7] |
徐爱蕾,王为.降钙素原检测方法学和临床意义的研究进展[J].临床军医杂志,2012,40(1):242-244.
|
[8] |
杨欣悦,钱传云,樊楚明.高敏C-反应蛋白与降钙素原对感染性疾病预后评估研究[J].中华医院感染学杂志,2014,24(1):22-24.
|
[9] |
齐英征,多力坤·木扎帕尔.降钙素原和D-二聚体对全身炎症反应综合征患儿病情预后的判断价值[J].中国当代儿科杂志,2014,16(4):384-388.
|
[10] |
贺彬,祝益民.降钙素原在小儿脓毒症中的应用[J].中国小儿急救医学,2013,20(3):324.
|
[11] |
王伟佳,张秀明,阚丽娟,等.降钙素原检测在感染性疾病诊断中的干扰研究[J].中华医院感染学杂志,2013,23(13):3048-3050,3053.
|
[12] |
Mussap M,Degrandi R,Cataldi L,et al.Biochemical markers for the early assessment of neonatal sepsis:the role of procalcitonin[J].J Chemother,2007,19(Suppl 2):35-38.
|
[13] |
张燕搏,王旭,王飞燕,等.降钙素原在婴幼儿体外循环术后感染监测中价值[J].中华实用诊断与治疗杂志,2012,26(2):116-117.
|
[14] |
李绍锦,李上淼,杨娇娇,等.检测降钙素原及超敏C-反应蛋白在新生儿感染的临床意义[J].中华医院感染学杂志,2012,22(10):2104-2105.
|
[15] |
任丽艳,陈涵强.降钙素原在早期诊断新生儿感染疾病中的临床意义[J].中国新生儿杂志,2009,24(2):125-128.
|
[16] |
贺彬,祝益民.降钙素原在小儿脓毒症中的应用[J].中国小儿急救医学,2013,20(3):324-326.
|
|
|
|