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Meta-analysis of Shensongyangxin Capsules treating viral myocarditis |
ZHANG Shu-dan1 LI Qi2 DU Chang-sheng1 |
1.Department of Pharmacy,Dalian Hospital of Traditional Chinese Medicine in Liaoning Province,Dalian116013,China;
2.Department of Internal Medicine,the Third Hospital of Wafangdian in Liaoning Province,Dalian116300,China |
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Abstract ObjectiveTo review systematically the effect and safety of Shensongyangxin Capsules treating viral myocarditis,and provide the related basis of evidence based medicine for Shensongyangxin Capsules treating viral myocarditis.MethodsPubMed,EMbase,Cochrane Library,CBM,WanFang,CNKI and VIP were retrieved using the computer for collecting RCT and CCT for database construction to November 4,2016,and all references included in the literature were traced.According to the inclusion and exclusion criteria,two reviewers screened and assessed independently the literature,and then the data was extracted.The data was given a Meta-analysis by using RevMan 5.3 software.Results12 study articles were included.Meta-analysis showed that the clinical curative effect of the Shensongyangxin group treating viral myocarditis was better than the Western medicine group(OR=3.19,95%CI:2.14-4.74,P<0.01).The clinical curative effect of the Shensongyangxin group treating ventricular arrhythmia was better than the Western medicine group(OR=3.64,95%CI:2.50-5.30,P<0.01).The occurrence rate of adverse events was lower and the reactions was low and mild in the Shensongyangxin group.ConclusionShensongyangxin Capsules has a significant curative effect treating viral myocarditis,and the safety is good.
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