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Effect of fluprofen tromethamine for refractory non-erosive gastroesophageal reflux disease |
LIU Feng1 LI Jun2▲ |
1.Nanping Judicial Coercive Isolation Center in Fujian Province,Nanping 353000,China;
2.Department of Gastroenterology,the Affiliated First Hospital of Nanping in Fujian Medical University,Nanping 353000,China |
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Abstract ObjectiveTo investigate the clinical effect of fluprofen tromethamine for refractory non-erosive gastroesophageal reflux disease.Methods80 cases with refractory non-erosive gastroesophageal reflux disease from January 2015 to January 2017 were randomly divided into two group,each 40 cases.The control group were treated with rabbits and the observation group were used flupaphene tromethamine tablets,and all were taken for 8 weeks for a course,then tolerance(RDQ)questionnaire,24 h and 48 h after treatment,pH values,adverse reactions and total hospital stay were compared.ResultsThe RDQ scores with heartbeat,posterior sternal pain,acid reflux and belching in the observation group were significantly lower than control group (P<0.05),the pH value in the observation group with 24 h and 48 h were significantly higher than control group (P<0.05).There had no significant difference in the incidence with dry mouth,tachycardia and vertebral body reaction between the two group (P>0.05),the hospital stay time in the observation group was significantly shorter than control group (P<0.05).ConclusionFor the treatment of refractory non-erosive gastroesophageal reflux disease,the treatment with fenaprozethillin can relieve the clinical symptoms and improve the pH value in the stomach and short the hospitalization time and the treat has less adverse reactions,so it is safe.
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[1] |
蒋义贵,尤丽财,张生君,等.黛力新治疗伴有焦虑及抑郁状态的非糜烂性胃食管反流病例[J].药物与临床,2014,(1):219-221.
|
[2] |
吴彦彦,李丽平.非糜烂性胃食管反流病患者应用兰索拉唑联合氟哌噻吨美利曲辛片治疗的临床疗效分析[J].中国实用医药,2015,10(32):159-160.
|
[3] |
郑光波,高向红,赵可检,等.氟哌噻吨美利曲辛辅治中重度非糜烂性胃食管反流病120例疗效观察[J].临床合理用药,2014,7(8):27.
|
[4] |
王亚雷,王伟伟,许建明.埃索美拉唑联合氟哌噻吨美利曲辛治疗难治性胃食管反流病的多中心临床观察研究[J].安徽医药,2015,19(10):2009-2011.
|
[5] |
刘恋.奥美拉唑联合氟哌噻吨美利曲辛治疗中重度非糜烂性胃食管反流病疗效[J].中国医药科学,2016,6(15):77-79.
|
[6] |
曾静.氟呱嘎吨美利曲辛辅助治疗难治性胃食管反流病的临床观察[J].世界最新医学信息文摘,2016,16(49):127-129.
|
[7] |
季兴,黄薇薇,程莉华,等.氟呱嘎吨美利曲辛联合埃索美拉哩治疗非糜烂性胃食管反流病的临床观察[J].中国药房,2013,24(8):711-713.
|
[8] |
王良晶,陈龙,徐岷.氟哌噻吨美利曲辛联合其他药物治疗非糜烂性胃食管反流病疗效的荟萃分析[J].用药指南,2015,(34):265-267.
|
[9] |
黄松林,李哮天.氟哌噻吨美利曲辛联合雷贝拉唑治疗非糜烂性胃食管反流病伴抑郁焦虑患者的疗效观察[J].广西医学,2017,39(1):100-102.
|
[10] |
陈晓锋,吴育龙,李秋元.氟哌噻吨美利曲辛联合埃索美拉唑治疗难治性胃食管反流病的临床疗效观察[J].中国当代医药,2016,23(4):38-43.
|
[11] |
丁西平,郭春丽,余跃,等.氟哌噻吨美利曲辛片联合?B?族维生素辅助治疗伴心理障碍的非糜烂性反流病临床疗效[J].中国临床保健杂志,2013,16(4):380-382.
|
[12] |
徐艳,王晓瑜.氟哌噻吨美利曲辛片辅助治疗难治性非糜烂性胃食管反流病的临床观察[J].临床消化病杂志,2016,(28):367-369.
|
[13] |
徐杲,华娴,徐希,等.氟哌噻吨美利曲辛联合质子泵抑制剂对伴焦虑抑郁的非糜烂性胃食管反流病的临床疗效[J].医学研究杂志,2016,45(1):138-162.
|
[14] |
侯慧,荣亮.氟哌噻吨美利曲辛联合质子泵抑制剂对伴焦虑抑郁的非糜烂性胃食管反流病的临床效果观察[J].胃肠病学和肝病学杂志,2014,23(7):755-758.
|
[15] |
赵昌东,张小节,张辉,等.心理干预联合黛力新治疗非糜烂性反流病伴精神心理障碍的临床研究[J].胃肠病学和肝病学杂志,2014,23(10):1152-1154.
|
[16] |
李坚,李璟寰,林煜光,等.胃食管返流病患者应用黛力新疗效观察[J].中国现代药物应用,2013,7(11):23-25.
|
[17] |
郭林林,唐捷.氟哌噻吨美利曲辛治疗伴焦虑或抑郁的非糜烂性胃食管反流病的疗效观察[J].中国执业药师,2016,13(3):9-12.
|
[18] |
杨勇.氟哌噻吨美利曲辛在伴有焦虑或抑郁的非糜烂性胃食管反流病中的临床应用[J].国际消化病杂志,2016,36(5):287-290.
|
|
|
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