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Effects of Shenxiong G lucose Injection in the treatment of acute cerebral infarction and its effect on nerve function and hemorrheology |
LIAO Hua-yin HU Qiong-li BAO Ze-yan ZHONG Shui-sheng |
The Second Departmentof Neurology,Guangdong 999 Brain Hospital in Guangdong Province,Guangzhou 510510,China |
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Abstract ObjectiveTo investigate effects of Shenxiong Glucose Injection in the treatment of acute cerebral infarction and its effect on nerve function and hemorrheology.Methods114 cases of acute cerebral infarction patients in our hospital from December 2014 to April 2016 were selected and randomly divided into research group and control group, 57 cases in each group.Patients in the control group were treated with Troxerutin brain protein hydrolyzate based on conventional therapy,patients in the research group were treated with Shenxiong Glucose Injection combined with Troxerutin brain protein hydrolyzate.The total effective rate,neurological deficit scores,hemorheolog parameter and SF-36 score for evaluating quality of life before and after treatment of two groups were compared.ResultsThe total effective rate in the research group was80.7%,higher than 61.4%in the control group,and the differencewas statistically significant(P<0.05).Therewere no significant difference in neurological deficit scores,hemorheolog parameter and SF-36 score before treatment(P>0.05).After treatment of 15,30 and 60 d,the neurological deficit scores in the research group was lower than that in the control group(P<0.05);after treatment,the hemorheolog parameter such aswhole blood highshear viscosity,whole blood low-shear viscosity,hematocrit,platelet aggregation of the research group was lower than that of the control group (P<0.05);the SF-36 score of the research group was higher than that of the control group,and the difference was statistically significant(P<0.05).ConclusionShenxiong Glucose Injection hasexacteffect in the treatment of acute cerebral infarction,which can effectively restore neurological function,improve hemorrheology,improve the quality of life of patients.It isworthy of clinical popularization and application.
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[1] |
牟鸣,张杰,沈志敏,等.参芎葡萄糖注射液联合脑蛋白水解物治疗急性脑梗塞的疗效及对神经功能缺损和血液流变学的影响[J].现代生物医学进展,2015,15(2):321-324.
|
[2] |
楚海波,董华丽,廉全荣,等.参芎葡萄糖注射液与依达拉奉治疗急性脑梗死54例疗效观察[J].中国实用神经疾病杂志,2012,15(15):36.
|
[3] |
姚冬杰,周淑芬,于涛.参芎葡萄糖注射液治疗短暂性脑缺血发作的临床分析[J].微量元素与健康研究,2013,8(3):15-16.
|
[4] |
胡仁琳,李鸣,张弦.参芎葡萄糖注射液联合依达拉奉对脑梗死患者血清HMGB1,ENA-78和S100β蛋白水平的影响[J].河北医药,2014,36(6):828-831.
|
[5] |
葛绪春,王文,耿德勤.参芎葡萄糖注射液对脑梗死患者血肿瘤坏死因子α的影响[J].中国实用神经疾病杂志,2015,18(9):116-117.
|
[6] |
王宏.参芎葡萄糖注射液治疗急性脑梗死后脑心综合征的疗效[J].中国实用神经疾病杂志,2013,16(13):78-80.
|
[7] |
王运良,李爱琴,卢月红,等.参芎葡萄糖注射液联合他汀辅酶治疗急性脑梗死68例疗效观察[J].中国医药指南,2013,11(14):216-217.
|
[8] |
曹红元,刘雨辉,李惠允,等.急性脑梗死后炎性因子的动态变化及其与神经功能的相关性研究[J].解放军医药杂志,2014,26(3):51-54.
|
[9] |
王传明,杨春水,李雯飞,等.静脉溶栓与机械取栓治疗急性脑梗死的临床疗效观察[J].现代医院,2015,15(8):15-17.
|
[10] |
商华,温黎青,王芳芳,等.槐杞黄颗粒联合参芎葡萄糖治疗难治性肾病综合征的临床研究[J].右江医学,2013,41(3):340-343.
|
[11] |
季一飞,龙继发,柳华,等.参芎葡萄糖注射液治疗急性脑梗塞临床疗效观察[J].河南中医,2013,33(4):131.
|
[12] |
张志坚,曹传勇.参芎葡萄糖注射液治疗急性脑梗死的疗效观察及其对血浆内皮素的影响[J].广东医学院学报,2008,26(4):408-409.
|
[13] |
肖承年,梁海山,黄鹏,等.丹红注射液对急性脑梗死患者神经功能及血液流变学的影响[J].中国当代医药,2014,21(29):66-68.
|
[14] |
邓语.参芎葡萄糖注射液对于心脑血管疾病的应用与疗效[J].中国医药指南,2015,13(8):157.
|
[15] |
吴佳苹,于海波.调任通督针刺法联合参芎葡萄糖注射液治疗前循环型脑梗死恢复期临床观察[J].山西中医,2016,32(6):24-27.
|
[16] |
张宏祥.参芎葡萄糖注射液治疗急性脑梗死的疗效观察[J].实用心脑肺血管病杂志,2014,22(10):88-89.
|
|
|
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