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Investigation of the immune prevention status and hepatitis B virus infection for preschool children in the Jiangcheng district of Yangjiang city |
LIN Ru-mei1 CHEN Wen-feng2 ZOU Hui-xiang1 |
1.Clinical Laboratory,Traditional Chinese Medicine Hospital of Yangjiang City in Guangdong Province,Yangjiang 529500,China;
2.Clinical Laboratory,Maternal and Child Health Care Hospital of Yangjiang City in Guangdong Province, Yangjiang 529500,China |
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Abstract Objective To explore the status of hepatitis B virus infection and hepatitis B vaccination among preschool children in Jiangcheng district of Yangjiang city. Methods 12 174 preschool children aged 3~6 in 21 public and private kindergartens in Jiangcheng district of Yangjiang city from April 2013 to April 2015 were selected and divided into grodeⅠ, gradeⅡand gradeⅢaccording to vaccination status of hepatitis B vaccine,the test data of hepatitis B virus serum markers(HBsAg,Anti-HBs). Results In the 12 174 preschool children,the positive rate of HBsAg and Anti-HBs was 0.74%and 86.74%respectively.The positive rate of HBsAg was 0.84%in male and 0.64%in female,there was no significant difference between different genders(P>0.05).The positive rate of HBsAg in gradeⅠwas lower than that gradeⅡand gradeⅢ,the positive rate of HBsAg in gradeⅡwas lower than that in gradeⅢ,with significant difference(P<0.05).The positive rate of Anti-HBs in gradeⅠwas higher than that gradeⅡand gradeⅢ,the positive rate of Anti-HBs in gradeⅡwas higher than that in gradeⅢ,with significant difference(P<0.05). Conclusion The infection rate is lower in preschool children in Jiangcheng district of Yangjiang city,and the rate of hepatitis B vaccine immunization and the positive rate of protective antibody(anti-HBs)in the serum are higher.
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