Abstract:Objective To investigate the application of metformin in polycystic ovary syndrome(PCOS),so as to provide a reference for clinical rational drug use.Methods The outpatient prescriptions of patients with diagnosed PCOS in Fujian Provincial Hospital from January 2018 to December 2019 were selected to analyze the use of metformin in PCOS prescriptions.Results A total of 282 PCOS prescriptions were selected,including 97 prescriptions with metformin monotherapy and 111 prescriptions with metformin combined with other drugs(103 for double combination and 8 for triple combination).The main drugs used in combination included dydrogesterone tablets,ethinylestradiol and cyproterone acetate tablets,pioglitazone hydrochloride tablets and spironolactone tablets.A total of 25 irrational prescriptions were found,mainly with inappropriate usage and dosage.Conclusion Metformin is mainly used in combination with other PCOS drugs in the treatment of PCOS.The combined use of drugs is basically rational,but there are still some unreasonable situations in dosage,frequency of administration and usage.
胡晓. 二甲双胍治疗多囊卵巢综合征的用药分析[J]. 中国当代医药, 2021, 28(13): 179-182.
HU Xiao. Analysis of medication for metformin in the treatment of polycystic ovary syndrome. 中国当代医药, 2021, 28(13): 179-182.