1021例精索静脉曲张患者附睾炎性肿块的临床研究

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摘要目的观察1021 例精索静脉曲张患者附睾炎性肿块的发生情况，探讨精索静脉曲张与附睾炎性肿块的关系。方法选取2011年12月～2015年5月郑州大学第一附属医院男科收治的1128 例男性不育患者作为研究对象，根据体格检查及阴囊超声结果，诊断患者有无精索静脉曲张、精索静脉曲张侧别、精索静脉曲张程度及附睾炎性肿块位置和数量，比较精索静脉曲张患者和非精索静脉曲张患者的附睾炎性肿块发生部位和发生率、不同精索静脉曲张侧别及不同精索静脉曲张程度患者的附睾炎性肿块发生率，并分析附睾炎性肿块对精索静脉曲张患者阴囊温度、性激素及精液质量的影响。结果精索静脉曲张患者1021 例，无精索静脉曲张患者107 例。精索静脉曲张患者附睾炎性肿块发生率高于非精索静脉曲张患者，差异有统计学意义（P<0.05）。单侧精索静脉曲张患者附睾炎性肿块发生率高于双侧精索静脉曲张患者，差异有统计学意义（P<0.05）。重度精索静脉曲张患者附睾体尾部炎性肿块发生率高于轻中度精索静脉曲张患者，差异有统计学意义（P<0.05）。精索静脉曲张有附睾炎性肿块患者与精索静脉曲张无附睾炎性肿块患者的精子浓度、精子总数及性激素水平比较，差异无统计学意义（P>0.05）。精索静脉曲张有附睾炎性肿块患者的阴囊温度高于精索静脉曲张无附睾炎性肿块患者，精子前向运动比例、精浆中性葡萄糖苷酶低于精索静脉曲张无附睾炎性肿块患者（P<0.05）。结论精索静脉曲张患者中附睾炎性肿块发生率显著升高，并且重度精索静脉曲张患者附睾体尾部炎性肿块发生率显著升高。与单纯精索静脉曲张比较，合并附睾炎性肿块的精索静脉曲张患者的中性葡萄糖苷酶水平较低，且对阴囊温度的影响更大，精子活力下降更明显。

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	王瑞
	吕坤龙
	郑涛
	张天标
	南永浩
	郝亚伟
	张杰

关键词 ：精索静脉曲张, 附睾炎性肿块, 男性不育, 精子

Abstract： Objective To observe the occurrence of epididymal inflammatory mass in 1021 patients with varicocele and explore the relationship between varicocele and epididymal inflammatory mass. Methods A total of 1128 male infertility patients who were admitted to the Department of Andrology in the First Affiliated Hospital of Zhengzhou University from December 2011 to May 2015 were selected as the research objects. The patients with varicocele were diagnosed,the side and degree of varicocele were distinguished, the location and number of epididymal inflammatory masses were recorded according to the results of physical examination and scrotal ultrasound. The location and incidence of epididymal inflammatory mass in patients with varicocele and non-varicocele, the incidence of epididymal inflammatory mass in patients with different varicocele side and different varicocele degrees were compared. The effects of epididymal inflammatory mass on scrotal temperature, sex hormones and semen quality in patients with varicocele were analyzed.Results There were 1021 cases in the varicocele group and 107 cases in the non-varicocele group. The incidence of epididymal inflammatory mass in the patients with varicocele was higher than that without varicocele, and the difference was statistically significant (P<0.05). The incidence of epididymal inflammatory mass in unilateral varicocele patients was higher than that in bilateral varicocele patients, and the difference was statistically significant (P<0.05). The incidence of epididymal caudal inflammatory masses in the severe varicocele patients was higher than that in the mild to moderate varicocele patients, and the difference was statistically significant (P<0.05). There were no significant differences in sperm concentration, total sperm count and sex hormone levels between the varicocele with epididymal inflammatory mass and the varicocele without epididymal inflammatory mass (P>0.05). The scrotal temperature of the varicocele with epididymal inflammatory mass was higher than that of the varicocele without epididymal inflammatory mass, the proportions of sperm forward movement and seminal plasma neutral glucosidase varicocele in patients with epididymal inflammatory mass were lower than those of the patients without epididymal inflammatory mass, and the differences were statistically significant (P<0.05). Conclusion The incidence of epididymal inflammatory masses in patients with varicocele significantly increase. The incidence of epididymal caudal inflammatory masses in the severe varicocele patients significantly increase. Compared with the varicocele patients without epididymal inflammatory mass,the varicocele patients with epididymal inflammatory mass has lower neutral glucosidase level, increase scrotal temperature and decrease sperm motility.

Key words： Varicocele Epididymal inflammatory mass Male infertility Sperm

引用本文:

王瑞；吕坤龙；郑涛；张天标；南永浩；郝亚伟；张杰. 1021例精索静脉曲张患者附睾炎性肿块的临床研究[J]. 中国当代医药, 2021, 28(3): 123-126.
WANG Rui1；LYU Kun-long； ZHENG Tao；ZHANG Tian-biao； NAN Yong-hao； HAO Ya-wei； ZHANG Jie. Clinical study of epididymal inflammatory mass in 1021 patients with varicocele. 中国当代医药, 2021, 28(3): 123-126.

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http://dangdaiyiyao.com/CN/ 或 http://dangdaiyiyao.com/CN/Y2021/V28/I3/123

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