Intervention effect analysis of clinical pharmacist reviewing on the unreasonable medical prescriptions of anti-tumor drugs in the vein configuration center
WEN Jian-kun HUANG Xiang-zhen ZHEN Ju-quan
Department of Pharmacy, Jiangmen Central Hospital, Guangdong Province, Jiangmen 529000, China
Abstract：Objective To analyze the intervention effect of clinical pharmacist reviewing on the unreasonable medical prescriptions of anti-tumor drugs in the vein configuration center. Methods The clinical drug system and hospital information system (HIS) were retrospectively analyzed. The anti-tumor drugs for inpatients in our hospital from January to June in 2018 were used to calculate the irrational use of drugs, as data before intervention. From July to December in 2018, clinical pharmacists participated in the medical reviewing, intervened when there were unreasonable medical prescriptions, and recorded the irrational use of drugs as data after intervention. The data obtained in the hospital throughout the year were statistically analyzed to compare the unreasonable medical prescriptions change of anti-tumor drugs before and after intervention and the effect of pharmacist intervention. Results The unreasonable rate of medical prescription after intervention was 3.28%, which was lower than 8.78% before intervention, with statistically significant difference (P＜0.05). There were statistically significant differences in the unreasonable rates of medical prescriptions of gynecology, otolaryngology, oncology, hepatobiliary gastrointestinal surgery, and thoracic surgery departments before and after intervention (P＜0.05). There were no significant differences in the unreasonable rates of medical prescriptions of radiotherapy and other departments before and after intervention (P＞0.05). Conclusion There are varied degrees of unreasonable medical prescriptions in different departments. Intervention by clinical pharmacists can effectively reduce the incidence of unreasonable anti-tumor drugs and avoid or reduce the incidence of adverse drug reactions.
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