Clinical effect of ultrasound-guided moving microwave ablation in the treatment of benign thyroid nodules
LUO Guo-qing ZHOU Jing-jing LI Guan-jie LI Si-wen LIANG Ji-huan LIU Qiu-hua XIA Xu HU Ning-dong
Department of Cardiothoracic Surgery, the Sixth Affiliated Hospital of Guangzhou Medical University People′s Hospital of Qingyuan City, Guangdong Province, Qingyuan 511500, China
Abstract：Objective To observe the clinical effect of ultrasound-guided moving microwave ablation in the treatment of benign thyroid nodules. Methods A total of 143 patients with thyroid nodules from July 2016 to August 2017 treated in our hospital were selected as research objects, and they were divided into the microwave ablation group (50 cases)and the traditional open surgery group (93 cases) according to different treatment methods. Ultrasound-guided moving microwave ablation was used in the microwave ablation group, while subtotal thyroidectomy was used in the traditional open surgery group. The operation time, bleeding volume, hospitalization time, hospitalization expenses, complications and the levels of thyroid stimulating hormone (TSH), free triiodothyronine (FT3), free tetraiodothyronine (FT4) before and after surgery were compared between the two groups. The volume of nodules was followed up at 1, 3, 6 and 12 months after ablation, and thyroid function was reexamined one month after ablation. Results The operation time and hospitalization time of the microwave ablation group were shorter than those of the traditional open surgery group, the amount of bleeding of the microwave ablation group was less than that of the traditional open surgery group, and the hospitalization cost of the microwave ablation group was higher than that of traditional open surgery group, with statistically significant differences (P＜0.01). There were no complications such as hoarseness and parathyroid injury in both groups.The total incidence rate of complications in the microwave ablation group was lower than that in the traditional open surgery group, and the difference was statistically significant (P＜0.05). There were no significant difference in the levels of TSH, FT3 and FT4 between the two groups before operation (P＞0.05). There were no significant differences in the levels of FT3 and TSH between the two groups one month after operation (P＞0.05). The level of FT4 in the microwave ablation group was higher than that before operation,and which was lower than that in the traditional open surgery group,the differences were statistically significant (P＜0.05). There was no significant difference in the goiter volume between preoperative and one month after microwave ablation (P＞0.05). Since 3 months after operation, the goiter volume had decreased significantly, the difference was statistically significant (P＜0.05). Conclusion Ultrasound-guided moving microwave ablation in the treatment of benign thyroid nodules has the advantages of short operation time, less bleeding during operation, short hospital stay, low incidence rate of complications and good surgical effect, which provides a new choice and approach for minimally invasive treatment of thyroid diseases in this area.
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