ObjectiveTo analyze the application of long-acting antibacterial material(JUC)in the care of local infection and skin allergy in patients with peripherally inserted central venous catheter.MethodsFrom June 2015 to June 2017,106 patients who receivedcentral venous catheter in our hospital were seleted and evenly divided into research group and control group by a random number table.In the control group,the puncture point of peripheral insertion of central venous catheter was covered by 3M transparent dressing,while in the research group,before covering 3M transparent dressing,long-acting antibacterial material was sprayed.The local infection and skin allergy after nursing were compared and analyzed in the two groups.ResultsSymptoms of local infection including sustained swelling and distension,abnormal secretion,pain or pressing pain after placement of central venous catheter.In the research group,the total local infection rate was 5.66%in patients with peripheral insertion of central venous catheter,much lower than that in the control group accounting for 26.52%,the difference was statistically significant(P＜0.05).Skin allergy like itching，rash or blister occurred in both groups.The total skin allergy rate was 9.43%，greatly lower than that in the control group(30.19%),the difference was statistically significant(P＜0.05).ConclusionSpraying JUC to the puncture point from peripheral insertion of central venous catheter before covering 3M transparent dressing remarkably decrease the local infection and skin allergy,which enhances patient′s confidence on early recovery,and is worthy of extensive application in clinic.