Abstract:Objective To investigate the short-term effect of celecoxib combined with CapeOX regimen in the treatment of advanced gastric cancer.Methods A total of 84 patients with advanced gastric cancer admitted to our hospital from May 2015 to November 2017 were selected and divided into control group and observation group according to the order of admission,with 42 cases in each group.The control group was treated with capeox regimen,while the observation group was treated with oral celecoxib on the basis of the control group.The incidence of adverse reactions and the total effective rate were compared between the two groups.Result The total effective rate in the observation group was significantly higher than that in the control group,the difference was statistically significant(P>0.05).The total incidence of adverse reactions in the observation group was significantly lower than that in the control group,the difference was statistically significant(P>0.05).Conclusion For patients with advanced gastric cancer,the combined method of Celecoxib and CapeOX can greatly reduce the adverse event rate,increase the effective rate,improve the life quality and extend the survival time.
杨海劲;田丹;吴剑. 塞来昔布联合CapeOX方案治疗晚期胃癌的近期效果[J]. 中国当代医药, 2018, 25(20): 57-59.
YANG Hai-jing;TIAN Dan;WU Jian. Short-term effect of celecoxib combined with CapeOX regimen in the treatment of advanced gastric cancer. 中国当代医药, 2018, 25(20): 57-59.