Influencing factors of the efficacy of the combination of Carboprost Trometham ine and Oxytocin in the treatment of postpartum hemorrhage after cesarean section
ZHAO Ya-ling
Department of Obstetrics and Gynecology,Chang′an Hospital in Dongguan City,Guangdong Province,Dongguan 523800,China
Abstract：ObjectiveTo explore the influencing factors of the efficacy of the combination of Carboprost Tromethamine and Oxytocin in the treatmentofpostpartum hemorrhageaftercesarean section.MethodsA retrospectiveanalysisof140 cases of cesarean section postpartum hemorrhage treated with Carboprost Tromethamine combined with Oxytocin in Chang′an Hospital in Dongguan City of Guangdong Province from September 2015 to September 2017 were carried out.According to the effect of clinical treatment,the patients were divided into effective group(n=120)and ineffective group(n=20).Single factor descriptive analysis and multiple factor Logistic regression analysis of factors that may affect the efficacy of such patients treated with Carboprost Tromethamine and Oxytocin were determined.ResultsThe rates of age≥35 years old,uterine scar pregnancy,multi fetus,fetal distress,double or multiple births,placenta previa,gestational times>3 and small pelvis in the ineffective group were much higher than those in the effective group,the differences were statistically significant(χ2=23.770,61.920,21.672,9.047,4.543,7.426,15.084,P<0.05).The age ≥35 years old,uterine scar pregnancy,multi fetus,fetal distress,double or multiple births,placenta previa,gestational times>3 and small pelvis were independent risk factors affecting the efficacy by Logistic regression analysis(OR=12.475,19.643,11.120,5.407,4.144,4.071,6.745,P<0.05).ConclusionThe greater the age,the less effective the treatment of postpartum hemorrhage treated with Carboprost Tromethamine combined with Oxytocin,in addition,there are a variety of risk factors that are more common.In order to promote the rapid recovery of postpartum hemorrhage in caesarean section and guarantee the recovery of postpartum hemorrhage,the strategies of improving the curative effect should be formulated according to the analysis of the above risk factors.
赵雅玲. 卡前列素氨丁三醇联合缩宫素治疗剖宫产产后出血效果的影响因素[J]. 中国当代医药, 2018, 25(17): 146-148转155.
ZHAO Ya-ling. Influencing factors of the efficacy of the combination of Carboprost Trometham ine and Oxytocin in the treatment of postpartum hemorrhage after cesarean section. 中国当代医药, 2018, 25(17): 146-148转155.
Caceda SI，Ramos RR，Saborido CM.Pharmacoeconomic study comparing carbetocin with oxytocin for the prevention of hemorrhage following cesarean delivery in Lima，Peru[J].J Comp Eff Res，2018，7（1）：49-55.
Volochovic J，Ramasauskaite D，Simkeviciūte R.Clinical aspects and antenatal diagnosis of invasive placenta：a review of ten-years′experience of a multi-profile hospital in Lithuania[J].Acta Med Litu，2017，24（3）：176-187.
京公网安备 11010502046607号