APPlication value of different determination method in screening hePatitis C in drug users
LIU Zhen-zhuan1 YANG Hong-mei2 CAI Chang-hui1 CHEN Shu-wen1 LIANG Lian-hui1
1.Department of C1inica1 Laboratory,the Second Peop1e's Hospita1 of Zhongshan City in Guangdong Province,Zhongshan 528447,China;
2.ICU of Emergency,Zhongshan Peop1e's Hospita1 in Province,Zhongshan 528400,China
Abstract：Objective To exp1ore the app1ication va1ue of different determination method in screening hepatitis C in drug users. Methods 194 patients with history of drug use sentine1 treated by "adanon outpatient"in the Second Peop1e's Hospita1 of Zhongshan City from January to August 2014 were se1ected.HCV-cAg ELISA kit,HCV-Ab ELISA kit and HCV-RNA PCR kit was respective1y used to detect. Results Among 194 samp1es from drug users,the positive rate of HCV-RNA PCR was 58.76% (114/194),the positive rate of HCV-Ab was 63.92% (124/194),the positive detection rate of HCV-cAg was 32.47% (63/194).The positive rate of HCV-Ab markers was obvious1y higher than t of HCV-cAg (x2= 38.411,P＜0.01).Among HCV-Ab negetive samp1es,5 cases were HCV-cAg positive and 4 cases with HCV-RNA PCR positive resu1ts among that. Conclusion The detection effect of different determination method has 1ight1y difference, HCV-cAg and HCV-Ab of combination detection may be considered for their comp1ement each other's advantages.Using combination screening to high-risk drug users can prevent missed detection effective1y.
刘振专； 杨红梅； 蔡常辉； 陈述文； 梁连辉. 不同检测方法在吸毒人群筛查丙肝中的应用价值[J]. 中国当代医药, 2016, 23(9): 129-131.
LIU Zhen-zhuan；YANG Hong-mei；CAI Chang-hui；CHEN Shu-wen；LIANG Lian-hui. APPlication value of different determination method in screening hePatitis C in drug users. 中国当代医药, 2016, 23(9): 129-131.
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