Effect comparison of Ambroxol Hydrochloride Tablet and Bromhexine Hydrochloride Tablet treating type 2 diabetes mellitus complicated with pulmonary infection
ZHAO Xin
Department of Internal Medicine,People′s Hospital of Chaoan District in Chaozhou City of Guangdong Province, Chaozhou521000,China
Abstract：Objective To compare the clinical effect of Ambroxol Hydrochloride Tablet and Bromhexine Hydrochloride Tablet treating type 2 diabetes mellitus complicated with pulmonary infection.Methods 80 patients with type 2 diabetes mellitus complicated with pulmonary infection treated by our outpatient of our hospital from October 2014 to February 2016 were selected.All patients were randomly divided into observation group and control group according to visiting ID number.All patients were given Piperacillin/Sulbactam for intravenous infusion,on the basis of Piperacillin-Sulbactam for intravenous infusion,patients in control group were given Ambroxol Hydrochloride Tablet and patients in observation group were given Bromhexine Hydrochloride Tablet.The clinical curative effect and treatment situation between two groups were compared.Results The disappearance time of fever in observation group[(1.51±0.41)h],cough disappeared time[(1.92±0.32)d]and hospitalization time[(12.1±2.9)d]was significantly shortened respectively compared with control group[(1.84±0.25)h,(2.14±0.43)h,(17.5±3.4)d](P<0.05);TNF-α[(155.21±23.54)pg/ml],procalcitonin[(0.24±0.03)ng/ml] and blood CRP[(6.42±1.32)mg/L]was significantly decreased respectively compared with control group[(201.35± 26.54)pg/ml,(0.31±0.04)ng/ml and(7.34±1.35)mg/L](P<0.01);the total effective rate of observation group(92.5%) was significantly higher than that of control group(72.5%)(P=0.044).Conclusion Ambroxol Hydrochloride Tablet combined with Piperacillin/Sulbactam for intravenous infusion can effectively treat lung infection of type 2 diabetes mellitus,and obviously shorten clinical symptom improvement time,promote faster recovery of patients and it is safe and feasible.It is can be promoted and applied in clinic.
京公网安备 11010502046607号