Abstract:Objective To analyze the changes of serum vitamin A levels in children with recurrent respiratory tract infection and its effects on immune function.Methods 100 cases of children with recurrent respiratory tract infection treated in our hospital from January 2014 to June 2015 were selected as the study group,and 100 healthy children in our hospital were taken as control group.The observation group was divided into observation group 1(n=40)and observation group 2(n=60).Children in the observation group were treated with conventional anti-infective therapy and the observation group 1 received vitamin A supplementation in addition.The levels of vitamin A and immune function of children in the control group were measured by microfluorescence,flow cytometry and automatic biochemical analyzer. The total effective rate of clinical treatment and the levels of IgA,IgM and IgG before and after treatment were compared between observation group 1 and observation group 2.Results The levels of vitamin A,IgA,IgM and IgG in the observation group were significantly higher than those in the control group(P<0.01).The total effective rate of clinical treatment in the observation group 1 was significantly higher than that in the observation group 2(P<0.01). There was no significant difference in the levels of IgA,IgM and IgG before treatment between observation group 1 and observation group 2(P>0.05).After treatment,Serum levels of IgM,IgG and IgA in observation group 1 were significantly higher than those in the observation group 2(P<0.01).Conclusion Children with recurrent respiratory tract infection have a lower level of serum vitamin A than healthy children.Vitamin A supplementation therapy for children with recurrent respiratory tract infection can enhance children′s immune function,get more significant therapeutic effect.
林凤姬. 反复呼吸道感染患儿血清维生素A水平及其对免疫功能的影响分析[J]. 中国当代医药, 2017, 24(3): 74-76.
LIN Feng-ji. Levels of serum vitamin A in children with recurrent respiratory tract infection and its impact on immune function. 中国当代医药, 2017, 24(3): 74-76.