Study of blood flows in main visceral organs of digestion and absorption in spleen yang deficiency and its underlying mechanism
QIAO Hai-feng1,2 LIU Wen-jun1 LIU Xu-dong1 WANG Ling-zhi1 LIU Hui-hui1 WANG De-shan1 SHAN De-hong1▲
1.Center Hospital of Chaoyang City in Liaoning Province,Chaoyang 122000,China;
2.Liaoning University of Traditional Chinese Medicine,Shenyang 110847,China
Abstract：ObjectiveTo study blood flow changes of main visceral organs of digestion and absorption in spleen yang deficiency and its possible mechanism from the ratio of thromboxane A2(TXA2)and prostacyclin(PGI2).Methods16 SPF rats were randomly divided into the control and the spleen yangdeficiency group(the model group),8 rats in each group. Laser speckle was used to detect blood flow changes in liver,pancreas,stomach,small intestine(SI)and its mesenterium. ELISA was employed to measure serum thromboxane A2(TXA2)and prostacyclin(PGI2)concentrations.ResultsCompared with those in the control group,blood flows inliver left and right lobes,pancreas,stomach and small intestine and TXA2/ PGI2(T/A)value were significantly increased in the model group(all P＜0.01),but blood flow of SI mesenterium and serum PGI2level were decreased obviously in the model group (all P＜0.01).ConclusionThere is enhancement of blood flows in main visceral organs of digestion and absorption in spleen yang deficiency,and its underlying mechanism might be attributed to the increase of T/P value.
乔海峰；刘文俊；刘旭东；王凌志；刘慧慧；王德山；单德红. 脾阳虚大鼠腹腔消化吸收结构表面微循环血流量变化及其机制研究[J]. 中国当代医药, 2017, 24(6): 109-111.
QIAO Hai-feng；LIU Wen-jun；LIU Xu-dong；WANG Ling-zhi；LIU Hui-hui；WANG De-shan；SHAN De-hong. Study of blood flows in main visceral organs of digestion and absorption in spleen yang deficiency and its underlying mechanism. 中国当代医药, 2017, 24(6): 109-111.
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