Abstract：Objective To investigate the epidemiological characteristics and drug use of human immunodeficiency virus(HIV) combined with tuberculosis (TB) infection. Methods A total of 79 patients with HIV complicated with TB infection in Jiujiang Third People's Hospital from June 2019 to December 2020 were selected for investigation, and the data of marital status, gender and drug abuse were analyzed. The risk factors of HIV complicated with TB infection were analyzed by multivariate logistic analysis, and drug use was analyzed. Results Univariate analysis showed that there were statistically significant differences among patients with different age, education background, infection route, NUMBER of CD4+cells and whether they knew TB was one of the common opportunistic infections of AIDS (P＜0.05). Multivariate analysis showed that age, educational background, infection route, CD4+ cell count and whether TB is one of the common opportunistic infections of AIDS were independent risk factors for HIV with TB infection (P＜0.05). The drug resistance rates of HIV combined with TB infection to eight drugs from high to low were Isoniazid, Rifampicin, Pyrazinamide, Levofloxacin, Protionamide, Rifapentine, Sodium Aminosalicylate, Ethambutol respectively. Conclusion It is necessary to increase the screening of HIV and TB among the low-educated and older people, and use drugs for treatment in response to drug resistance.
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