Objective To explore the effect of manual reduction splint combined with plaster external fixation in the treatment of triplane fracture of distal tibia in adolescents.Methods The clinical data of 58 adolescent patients with triplane fracture of the distal tibia who were admitted to Guangzhou Bone Setting Hospital from January 2015 to December 2018 were retrospectively analyzed,and they were divided into the treatment group and the control group according to different treatment method,with 29 cases in each group.The treatment group was treated with manual reduction splint combined with plaster external fixation,while the control group was treated with open reduction and internal fixation.Clinical efficacy,adverse reactions and fracture healing time were compared between the two groups.Results All patients were followed up for 6 to 18 months,with an average of 11 months.There was no statistically significant difference in the excellent and good rate of treatment between the two groups(P＜0.05).The incidence of adverse reactions in the treatment group was lower than that in the control group,and the difference was statistically significant(P＜0.05).The fracture healing time in the treatment group was shorter than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion Manual reduction splint combined with plaster external fixation in the treatment of triplane fracture of distal tibia has significant clinical effect and is worthy of clinical promotion and application.