Abstract：Objective To explore the correlation between the changes of waistline and set-up errors of two kinds of immobilization methods in cervical cancer radiotherapy.Methods A total of 60 patients with cervical cancer who received radiotherapy in the First Affiliated Hospital, Sun Yat-sen University from June to December 2019 were retrospectively selected and divided into group A and group B according to the supine or prone position, with 30 cases in each group.Cone beam CT (CBCT) was performed once a week.The set-up errors of translation, rotation and waistline were recorded offline, and the correlation between the changes of waistline and set-up errors were calculated.Results The translation errors of X, Y and Z directions in group A were (-0.5±2.7), (-0.1±3.2), (-0.4±2.5) mm, and (-0.2±3.0),(-0.2±4.0), (2.0±4.1) mm in group B; the rotation errors of Rx, Ry and Rz in group A were (-0.6±2.2), (-0.2±0.8), (0.1±0.8)°, and (0.5±2.3), (-0.2±1.3), (0.5±0.9)° in group B.In Z, Rx and Rz directions, the difference between two groups was statistically significant (P＜0.05).The change of waistline △C in group A and B was (-2.3±2.7) and (-1.4±2.0) cm respectively, the difference between two groups was statistically significant (P＜0.05).There was a negative correlation between error of Z direction in group B and change of waistline △C (r=-0.618, P＜0.05).Conclusion In the supine position of cervical cancer radiotherapy, the repeatability is better, but the change of waistline will lead to serious adverse reactions.In the prone position, the protection of small bowel is better, but the change of waistline has a greater impact on the accuracy of Z direction.In clinic, the change of waistline should be paid attention and intervention of bladder filling and weight should be taken if necessary.
钟嘉健; 丘敏敏; 林泽煌; 黄泰茗; 闵蒙真; 肖振华; 邓永锦. 宫颈癌放疗腰围变化与两种体位的相关性研究[J]. 中国当代医药, 2021, 28(10): 159-162.
ZHONG Jia-jian; QIU Min-min; LIN Ze-huang; HUANG Tai-ming; MIN Meng-zhen; XIAO Zhen-hua; DENG Yong-jin. Study on the correlation between the changes of waistline and two kinds of immobilization methods in cervical cancer radiotherapy. 中国当代医药, 2021, 28(10): 159-162.
Wang S，Shan S，Chen J，et al.Dosimetric Effects of Bladder Filling Volume on Small Bowel in Intensity-Modulated Radiation Therapy Treatment Planning of External Beam Radiation Therapy for Cervical Cancer[J].Int J Radiat Oncol，2017，99（2）：E644.
[3]
Stromberger C，Kom Y，Kawgan-Kagan M，et al.Intensity-Modulated Radiotherapy in Patients with Cervical Cancer.An intra-individual Comparison of Prone and Supine Positioning[J].Radiat Oncol，2010，5：63.
Weiss E，Richter S，Hess CF.Radiation therapy of the pelvic and paraaortic lymph nodes in cervical carcinoma：a prospective three-dimensional analysis of patient positioning and treatment technique[J].Radiother Oncol，2003，68（1）：41-49.
[17]
Chen VE，Gillespie EF，Manger RP，et al.The impact of daily bladder filling on small bowel dose for intensity modulated radiation therapy for cervical cancer[J].Med Dosim，2019，44（2）：102-106.
京公网安备 11010502046607号