Abstract：Objective To explore the clinical value of minimally invasive percutaneous nephrolithotomy (mPCNL) combined with flexible ureteroscopy in the treatment of complex kidney stones, and to provide guidance for optimizing the treatment plan.Methods A total of 60 patients with complicated kidney stones admitted in Xingang Central Hospital from January 2018 to December 2019 were selected as the research objects and divided into the control group and the study group according to the random number table method, with 30 cases in each group.The control group chose standard channel percutaneous nephroscope holmium laser lithotripsy, and the study group chose mPCNL combined with flexible ureteroscope holmium laser lithotripsy.The perioperative changes in related indicators, the levels of serum cortisol (Cor) and C-reactive protein (CRP) before and the next day after the operation, the urinary tract infections and stone clearance counted 3 days after the operation of two groups were compared.Results The operation time of the study group was longer than that of the control group, and the blood loss during operation was fewer than that of the control group, the postoperative hospital stay was shoter than that of the control group, the differences were statistically significant (P＜0.05).The comparison of serum Cor and CRP before operation between the two groups was not statistically significant (P＞0.05).The serum levels of Cor and CRP on the next day after surgery were lower than those before surgery, and the above indicators of the study group were lower than those of the control group, the differences were statistically significant(P＜0.05).The incidence of urinary tract infection in the study group was lower than that in the control group, and the stone clearance rate was higher than that in the control group, the differences were statistically significant (P＜0.05).Conclusion The mPCNL combined with flexible ureteroscopy for patients with complex kidney stones has a better effect, which can control and reduce intraoperative blood loss, shorten postoperative hospital stay, reduce serum Cor and CRP levels and the risk of urinary tract infections, and improve stone removal.
京公网安备 11010502046607号