Effect comparison of Low Molecular Weight Heparin Calcium with different injection methods in the treatment of venous crisis of pedicle flap
WU Yao-qiang1 CHEN Ning1 LAI Sheng-hua2 ZHOU Li-zhi3
1.Department of Hand Surgery,Machong Hospital of Dongguan City in Guangdong Province,Dongguan 523142,China;2.Clinical Laboratory,Machong Hospital of Dongguan City in Guangdong Province,Dongguan 523142,China;3.Department of Pharmacy,Machong Hospital of Dongguan City in Guangdong Province,Dongguan 523142,China
Abstract：Objective To compare the effect of Low Molecular Weight Heparin Calcium with different injection methods in the treatment of venous crisis of pedicle flaps.Methods A total of 50 patients with venous crisis of pedicle flap in our hospital from February 2017 to February 2018 were randomly selected as the research objects.According to the different injection methods of Low Molecular Weight Heparin Calcium,they were divided into local subdermal injection in flap congestion area plus bloodletting with a small incision group(the flap congestion area group,n=25)and umbilical subcutaneous injection plus bloodletting with a small incision in the flap congestion area group (the umbilical group,n=25).The flap necrosis rate,activated partial thromboplastin time (APTT),and hematoma under the flap were statistically compared between the two groups.Results The flap necrosis rate in the flap congestion area group was significantly lower than that in the umbilical group,and the difference was statistically significant(P＜0.05).The APTT in the flap congestion area group was significantly shorter than that in the umbilical group,and the difference was statistically significant(P＜0.05).However,there was no significant difference in the incidence of subcutaneous hematoma between the two groups(P＞0.05).Conclusion Compared with umbilical subcutaneous injection plus bloodletting with a small incision in the flap congestion area,Low Molecular Weight Heparin Calcium with local subdermal injection in flap congestion area plus bloodletting with a small incision obtains a better effect on treating venous crisis of pedicle flap.
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