[13] |
Wullschleger S,Loewith R,Hall MN.TOR Signaling in growth and metabolism[J].Cell,2006,124(3):471-484.
|
[16] |
张丹丹,李庆林.PI3K/Akt/mTOR信号通路与肿瘤[J].安徽医药,2012,16(3):281-282.
|
[17] |
张慧锋,李妍,白雪,等.mTOR信号通路及其抑制剂的研究进展[J].中国畜牧兽医,2013,40(2):36-41.
|
[20] |
翟纯刚,季晓平,陈文强.自体吞噬在动脉粥样硬化斑块中的作用[J].国际心血管病杂志,2013,40(3):142-144.
|
[23] |
常立功,黄培林.mTOR信号通路与大肠癌演进相关性的研究进展[J].东南大学学报(医学版),2013,32(2):243-247.
|
[1] |
沈武钢,邱晓平.脑梗死与脑出血患者的相关危险因素对比研究[J].临床和实验医学杂志,2010,9(1):14-15.
|
[2] |
Yorimitsu T,Klionsky DJ.Autophagy:Molecular machinery for self-eating[J].Cell Death Differ,2005,12(S2):1542-1552.
|
[6] |
Baehrecke EH.Autophagic programmed celldeath in drosophila[J].Cell Death Differ,2003,10(9):940-945.
|
[8] |
李键,秦宣锋,徐锋.自噬在小鼠缺血再灌注损伤中的作用[J].中华实验外科杂志,2013,30(9):1853-1855.
|
[10] |
JungCH,Ro SH,Cao J,et al.mTORregulation of autophagy[J].FEBS Lett,2010,584(7):1287-95.
|
[11] |
Guertin DA,Sabatini DM.Defining the role of mTOR in cancer[J].Cancer Cell,2007,12(1):9-22.
|
[3] |
Swampillai AL,Salomoni P,Short SC.The role of autophagy in clini-cal practice[J].Clin Oncol(R Coll Radiol),2012,24(6):387-395.
|
[4] |
Wang DW,Peng ZJ,Ren GF,et al.The different roles of selective autophagic protein degradation in mammalian cells[J].Oncotarget,2015,6(35):37098-37116.
|
[5] |
Whitehead NP.Enhanced autophagy as a potential mechanism for the improved physiological function by simvastatin in muscular dystrophy[J].Autophagy,2016,12(4):705-706.
|
[7] |
Chen Y,Mcmillanward E,Kong J,et al.Oxidative stressinduces autophagic cell death independent of apoptosisin transformed and cancer cells[J].Cell Death Differ,2008,15(1):171-182.
|
[9] |
Wang JY,Xia Q,Chu KT,et al.Severe global cerebralischemia-induced programmed necrosis of hippocampal CA1 neurons in rat is prevented by 3-Methyladenine:a widely used inhibitor of autophagy[J].J Neuropathol Exp Neurol,2011,70(4):314-322.
|
[12] |
Jacinto E,Loewith R,Schmidt A,et al.Mammalian mTOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive[J].Nat Cell Biol,2004,6(11):1122-1128.
|
[14] |
Altman JK,Yoon P,Katsoulidis E,et al.Regulatory effects of mammalian target of rapamycin-mediated signalsin the generation of arsenic trioxide responses[J].J Biol Chem,2008,283(4):1992-2001.
|
[15] |
Sinnberg T,Lasithiotakis K,Niessner H,et al.Inhibitionof PI3K-AKT-mTOR signaling sensitizes melanoma cells tocisplatin and temozolomide[J].J Invest Dermatol,2009,129(6):1500-1515.
|
[18] |
Vander HE,Lee S,Bandhakavi S,et al.Insulin signallingto mTOR mediated by the Akt/PKB substrate PRAS40[J].Nat Cell Biol,2007,9(3):316-323.
|
[19] |
Inoki K,Li Y,Zhu T,et al.TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signaling[J].Nat Cell Biol,2002,4(9):648-657.
|
[21] |
Zhang L,Niu WX,He ZJ,et al.Autophagy suppression by exercise pretreatment and p38 inhibition is neuroprotective in cerebralischemia[J].Brain Res,2014,1587(4):127-132.
|
[22] |
Xiao YZ,Liu H,Yu JJ,et al.Activation of ERK1/2 amelioratesliver steatosis in lepin receptor deficient(db/db)mice via stimulating ATG7-dependent autophagy[J].Diabetes,2016,65(2):393-405.
|
[24] |
Deyoung MP,Horak P,Sofer A,et al.Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling[J].Genes Dev,2008,22(2):239-251.
|
[25] |
Maiuri MC,Galluzzi L,Morselli E,et al.Autophagy regulationby p53[J].Curr Opin Cell Biol,2010,22(2):181-185.
|
[26] |
Tasdemir E,Maiuri MC,Galluzzi L,et al.Regulation of autophagybycytoplasmicp53[J].NatCellBiol,2008,10(6):676-687.
|
[27] |
Lomonosova E,Chinnadurai G.BH3-only proteins in apoptosis and beyond:an overview[J].Oncogene,2008,27(1):2-19.
|