Clinical research on combination of app lication of Jiuer gingivitis flusher and diarrhea spleen powder in the treatment of patients with aphthous ulceration
XU Yun1 GAO Tong-tong2
1.Integrated Chinese and Western Medicine Hospital of Nanchang City，Nanchang 330003，China；
2.Open University of Jiangsu，Nanjing 210039，China
Abstract：Objective To investigate the clinical effect of combination of application of Jiuer Gingivitis Flusher and diarrhea spleen powder in the treatment of patients with aphthous ulceration.Methods A total of 80 patients with aphthous ulceration who were treated in department of stomatology in the hospital from March 2014 to March 2016 were selected and divided into two groups（control group and observation group）according to the random number table method，with 40 cases in each group.The control group was treated with chinese medicine Diarrhea spleen powder；while，the observation group was administered with Jiuer gingivitis flusher on the basis of Diarrhea spleen powder.The results of two groups were compared.Results The total effective rate of aphthous ulceration patients in observation group and control group was 97.5%and 70%respectively，with statisticant difference（P＜0.01）.The pre-treatment aphthous ulceration pain score，the number and diameter of aphthous ulceration of two groups showed no obvious significant difference（P＞0.05）and were decreased in comparison with post-treatment ones，with significant difference （P＜0.05）.But amore obvious decrease was seen in observation group，with significant difference（P＜0.05）.Only 1 case of xerostomia occurred in observation group with adverse reaction rate accounting for 2.5%versus control group′s 17.5% （mild mucosal irritation in 2 cases，1 case of local swelling and 4 cases of xerostomia），with significant difference（P＜0.05）.Conclusion Combination of application of Jiuer gingivitis flusher and Diarrhea spleen powder demonstratesmore remarkable clinical effects in the treatment of patients with aphthous ulceration，obvious alleviation of patients′headache，elimination of related symptoms and reduction of adverse reaction rates，which is of remarkable significance to guarantee the quality of life for patients and deserveswider population.
许云;高彤彤. 九尔口爽含漱联合泻脾散治疗口疮患者的临床效果研究[J]. 中国当代医药, 2016, 23(25): 120-122.
XU Yun;GAO Tong-tong. Clinical research on combination of app lication of Jiuer gingivitis flusher and diarrhea spleen powder in the treatment of patients with aphthous ulceration. 中国当代医药, 2016, 23(25): 120-122.
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