急性CO中毒致心肌损害及早期干预与预后的临床研究

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Abstract Objective To investigate the clinical effect of acute carbon monoxide(CO)poisoning on myocardial damage and early intervention and prognosis.Methods Clinical data of 90 patients with myocardial damage caused by acute CO poisoning admitted to People′s Hospital of Xinyu City,Jiangxi Province from June 2017 to June 2020 were retrospectively analyzed and divided into intervention group and control group according to different treatment methods,with 45 cases in each group.Patients of both groups received conventional symptomatic and supportive treatment.On this basis,the intervention group received early hyperbaric oxygen therapy,and the control group received late hyperbaric oxygen therapy.Both groups received continuous treatment for 14 days.The clinical efficacy,clinical indicators,cardiac troponin T(cTnT)and myocardial enzyme spectrum were compared between the two groups.Results The total effective rate of treatment in the intervention group was higher than that in the control group,the recovery time and hospitalization time were shorter than those in the control group,hyperbaric oxygen chamber treatment times was less than that of the control group,and the differences were statistically significant(P＜0.05).After treatment,the levels of cTnT,creatine kinase(CK),aspartate aminotransferase(AST),lactate dehydrogenase(LDH)and creatine kinase isoenzyme(CKMB)in the groups were lower than those before treatment,and the differences were statistically significant(P＜0.05).After treatment,the levels of cTnT,CK,AST,LDH and CK-MB in the intervention group were lower than those in the control group,and the differences were statistically significant(P＜0.05).Conclusion Early hyperbaric oxygen treatment of patients with myocardial damage caused by acute CO poisoning can effectively improve the patient′s condition,improve cTnT and myocardial enzyme spectrum indicators,reduce the number of hyperbaric oxygen treatments,and shorten the recovery time and hospitalization time.It is worthy of clinical promotion.

Key words： Acute carbon monoxide poisoning Hyperbaric oxygen Myocardial damage Myocardial enzyme spectrum Cardiac troponin T

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	Articles by authors
	LIAO Yong
	AI Qing-ya
	LIAO Yu
	LIU Fei
	ZHONG Xue-fei
	XIA Hou-zong

Cite this article:

LIAO Yong,AI Qing-ya,LIAO Yu, et al. Clinical study on myocardial damage caused by acute CO poisoning and early intervention and prognosis[J]. 中国当代医药, 2021, 28(15): 70-72转76.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I15/70

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