奥曲肽、泮托拉唑联合生大黄在急性胰腺炎患者中的应用

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Abstract Objective To explore the application of Octreotide and Pantoprazole combined with Raw Rhubarb in patients with acute pancreatitis.Methods A total of 60 patients with acute pancreatitis treated in our hospital from January 2017 to January 2019 were selected as research subjects.They were divided into a control group (n=30)and observation group (n=30)by themethod of touching a ball at random.Patients in the control group were treated with Octreotide in combination with oral administration of Raw Rhubarb.In the observation group,participants were treated with Octreotide in combination with Pantoprazole and oral administration of Raw Rhubarb.The changes of abdominal distension disappearance time,abdominal pain disappearance time,bowel sounds recovery time,time for blood glucose to return to normal,healthy life scores and inflammatory factor levels in the two groupswere compared.Results In the observation group,the abdominal distension disappearance time,abdominal pain disappearance time,bowel sounds recovery time,time for blood glucose to return to normalwere shorter than those of the control group,and the differences were statistically significant(P＜0.05).The healthy life scores of the observation group after 3,6,12days after treatment were lower than those of the control group,and the differences were statistically significant(P＜0.05).After treatment,the levels of tumor necrosis factor-α(TNF-α)and interleukin-6(IL-6)in the observation group were lower than those of the control group,the differences were statistically significant(P＜0.05).Conclusion Treating patients with acute pancreatitis by taking Octreotide combined with Pantoprazole and oral administration of Raw Rhubarb can effectively shorten the time of symptom alleviation,improve the quality of healthy life and control tumor necrosis factor,which has a great value of clinical application.

Key words： Octreotide Pantoprazole Raw Rhubarb Acute pancreatitis Disappearance of abdominal pain

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	XU Wei-xi
	XU Xi-lin
	YAO Qiu-ping

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XU Wei-xi,XU Xi-lin,YAO Qiu-ping. Application of Octreotide and Pantoprazole combined with Raw Rhubarb in patients with acute pancreatitis[J]. 中国当代医药, 2020, 27(17): 43-45转53.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2020/V27/I17/43

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