不同前交通动脉瘤直回切除范围在前交通动脉瘤患者中的应用效果

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Abstract Objective To investigate the application effect of different anterior communicating aneurysms direct resection scope in patients with anterior communicating aneurysms. Methods A total of 52 patients with anterior communicating aneurysms admitted to our hospital from January 2017 to January 2018 were enrolled. The patients were divided into control group (22 cases) and study group (30 cases) according to different resection areas. The patients in the control group were treated with standard direct resection (resection range ≤1 cm3),and the patients in the study group were treated with a large range of direct resection (resection range ＞1 cm3). At the same time, 30 healthy people with normal physical examination results were selected as the healthy group. The probability of cognitive dysfunction between the control group and the study group was compared, and scores of mini-mental state examination (MMSE) and memory(simplified Rey-Osterreith complex figure test [ROCFT], World Health Organization-University of California Los Angeles auditory vocabulary learning test [WHO-UCLAAVLT]) were compared among the three groups. Results The probability of cognitive dysfunction in the study group was higher than that in the control group, and the difference was statistically significant (P＜0.05). The recall ability, memory ability, language ability, computing ability and attention, orientation and total scores of MMSE in the study group were lower than those in the control group and in the healthy group, the recall ability, memory ability, language ability, computing ability and attention, orientation and total scores of MMSE in the control group were lower than those in the healthy group, and the differences were statistically significant(P＜0.05). The simplified ROCFT scores such as word recognition, immediate memory and long-term delayed memory of the study group were lower than those of the control group and the healthy group, the simplified ROCFT scores of the control group such as word recognition, immediate memory and long-delayed memory were lower than those of the healthy group, with statistically significant differences (P＜0.05). The WHO-UCLAAVLT scores such as short-term delayed memory, long-term delayed memory and immediate memory of the study group were lower than those of the control group and the healthy group, the WHO-UCLAAVLT scores such as short-term delayed memory, long-term delayed memory and immediate memory of the control group were lower than those of the healthy group, and the differences were statistically significant (P＜0.05). Conclusion The influence of cognitive impairment is not obvious when the direct resection of the anterior communicating aneurysm scope is smaller. A larger scope direct anterior communicating aneurysm has a greater impact on the postoperative cognitive impairment. The scope of direct aneurysm resection has a certain impact on postoperative cognitive impairment.

Key words： Anterior communicating aneurysm Scope of direct resection Postoperative cognitive impairment Minimental state examination Language ability Memory score

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	ZHANG Hai-yang

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ZHANG Hai-yang. Application effect of different anterior communicating aneurysms direct resection scope in patients with anterior communicating aneurysms[J]. 中国当代医药, 2020, 27(16): 67-70转74.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2020/V27/I16/67

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