经颅磁刺激治疗精神分裂症患者的效果

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Abstract Objective To explore the effect of transcranial magnetic stimulation in the treatment of schizophrenia.Methods From March 2016 to March 2018, 112 patients with schizophrenia treated in our hospital were selected as the research objects.They were randomly divided into control group and study group by double color sphere method, with 56 patients in each group.Patients in the control group were given drug therapy, and patients in the study group were treated with transcranial magnetic stimulation on the basis of the control group.The clinical efficacy of the two groups after treatment was compared and analyzed.And the cognitive function and mental symptoms before and after treatment were compared between the two groups. Results The total effective rate of clinical treatment in the observation group was 98.21%, which was higher than that in the control group (78.57%), the difference was statistically significant (P＜0.05).Before treatment, there were no significant differences in the scores of positive symptoms, negative symptoms,general psychopathological symptoms and the total score of positive and negative syndrome scale (PANSS) between the two groups (P＞0.05).After treatment, the scores of positive symptoms, negative symptoms, general psychopathological symptoms and the total score of PANSS in the two groups were lower than those before treatment, and the scores of positive symptoms, negative symptoms, general psychopathological symptoms and the total score of PANSS in the observation group were lower than those of the control group, the differences were statistically significant (P＜0.05).Before treatment, there were no significant differences in invisual spatial working memory (VSWM) and vocabulary fluency(VFT) scores between the two groups (P＞0.05).After treatment, the VSWM and VFT scores of both groups were higher than those before treatment, and the VSWM and VFT scores in the observation group were higher than those in the control group, with statistically significant differences (P＜0.05). Conclusion The effect of transcranial magnetic stimulation on schizophrenia is remarkable, which can obviously improve the mental symptoms and cognitive function of schizophrenia, which is worth popularizing in clinic.

Key words： Schizophrenia Transcranial magnetic stimulation Mental symptoms

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	Articles by authors
	LIU Jia
	LIU Ya-li
	DONG Xian-miao
	WANG Mei
	ZHAO Lei

Cite this article:

LIU Jia,LIU Ya-li,DONG Xian-miao, et al. Effect of transcranial magnetic stimulation in the treatment of patients with schizophrenia[J]. 中国当代医药, 2020, 27(15): 63-65转69.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2020/V27/I15/63

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